中国医院统计
中國醫院統計
중국의원통계
Chinese Journal of Hospital Statistics
2015年
5期
340-342
,共3页
哮喘%儿童%过敏原%血清过敏原%皮肤过敏原
哮喘%兒童%過敏原%血清過敏原%皮膚過敏原
효천%인동%과민원%혈청과민원%피부과민원
Asthma%Children%Allergen%Serum allergen%Skin allergy
目的：探讨儿童哮喘的过敏原特征及其临床检测意义。方法采用病例对照的研究方法，对135例哮喘患儿和140例健康体检儿童分别进行问卷调查、皮肤点刺试验、血清过敏原检测等，比较分析2组的吸入性过敏原和食物性过敏原的阳性率、哮喘既往家族史及过敏性疾病史、血清学IgE阳性率等。结果哮喘组的尘螨、花粉、猫狗皮毛屑、羽毛、德国小蠊、牛奶、鸡蛋白、肉类等过敏原阳性率均明显高于对照组(P<0.05)；多因素分析显示，家族过敏史(OR=3.662)、一级亲属哮喘史(OR=8.388)、二级亲属哮喘史(OR=5.775)、过敏性鼻炎史(OR=5.569)、药物过敏史(OR=7.942)、湿疹史(OR=6.716)均为哮喘发病的危险因素；哮喘组的血清TIgE、SIgE阳性率分别为48.1％、65.2％，均明显高于对照组的22.9％、27.1％(均为P<0.01)。结论影响儿童哮喘发病的因素包括哮喘家族史、家族过敏史、湿疹史、吸入性过敏原、食物性过敏原，皮肤点刺试验和血清IgE对检测儿童哮喘过敏原具有重要的意义。
目的：探討兒童哮喘的過敏原特徵及其臨床檢測意義。方法採用病例對照的研究方法，對135例哮喘患兒和140例健康體檢兒童分彆進行問捲調查、皮膚點刺試驗、血清過敏原檢測等，比較分析2組的吸入性過敏原和食物性過敏原的暘性率、哮喘既往傢族史及過敏性疾病史、血清學IgE暘性率等。結果哮喘組的塵螨、花粉、貓狗皮毛屑、羽毛、德國小蠊、牛奶、鷄蛋白、肉類等過敏原暘性率均明顯高于對照組(P<0.05)；多因素分析顯示，傢族過敏史(OR=3.662)、一級親屬哮喘史(OR=8.388)、二級親屬哮喘史(OR=5.775)、過敏性鼻炎史(OR=5.569)、藥物過敏史(OR=7.942)、濕疹史(OR=6.716)均為哮喘髮病的危險因素；哮喘組的血清TIgE、SIgE暘性率分彆為48.1％、65.2％，均明顯高于對照組的22.9％、27.1％(均為P<0.01)。結論影響兒童哮喘髮病的因素包括哮喘傢族史、傢族過敏史、濕疹史、吸入性過敏原、食物性過敏原，皮膚點刺試驗和血清IgE對檢測兒童哮喘過敏原具有重要的意義。
목적：탐토인동효천적과민원특정급기림상검측의의。방법채용병례대조적연구방법，대135례효천환인화140례건강체검인동분별진행문권조사、피부점자시험、혈청과민원검측등，비교분석2조적흡입성과민원화식물성과민원적양성솔、효천기왕가족사급과민성질병사、혈청학IgE양성솔등。결과효천조적진만、화분、묘구피모설、우모、덕국소렴、우내、계단백、육류등과민원양성솔균명현고우대조조(P<0.05)；다인소분석현시，가족과민사(OR=3.662)、일급친속효천사(OR=8.388)、이급친속효천사(OR=5.775)、과민성비염사(OR=5.569)、약물과민사(OR=7.942)、습진사(OR=6.716)균위효천발병적위험인소；효천조적혈청TIgE、SIgE양성솔분별위48.1％、65.2％，균명현고우대조조적22.9％、27.1％(균위P<0.01)。결론영향인동효천발병적인소포괄효천가족사、가족과민사、습진사、흡입성과민원、식물성과민원，피부점자시험화혈청IgE대검측인동효천과민원구유중요적의의。
Objective To explore allergen characteristic and clinical detection meaning of children asthma. Methods With case-control study method, 135 children with asthma and 140 healthy children through physical examination were respec-tively accepted questionnaire investigation, skin prick test and serum allergen detection. The positive rates of inhaled allergens and food allergens, family history of asthma and history of hypersensitivity disease, IgE positive rate of serum were compared be-tween the two groups. Results The positive rates of allergen such as dust mite, pollen, cat dog dander, plumery, Blattella ger-manica, milk, egg white and flesh in the asthma group were much higher than those of the control group (P<0. 05). Multiple factors analysis result showed that these factors of family history of allergy (OR=3. 662), history of asthma of first-degree relative (OR=8. 388), history of asthma of second-degree relative (OR=5. 775), allergic rhinitis history (OR=5. 569), drug allergy history (OR=7. 942) and eczema history (OR=6. 716) in the asthma group were much higher than those of the control group (P<0. 01). The positive rates of TIgE and SIgE in the asthma group were respectively 48. 1% and 65. 2%, both much higher than those of the control group (22. 9% and 27. 1%, both P<0. 01). Conclusion The influencing factors of asthma include family history of asthma, family history of allergy, eczema history, inhaled allergens and food allergens. Skin prick test and serum IgE detection play an important role in detecting allergen of children asthma.
