CAJ | 학술논문

目的：探讨活血利水中药复方联合西药对于高血压早期肾损害的临床疗效。方法：选取2013年7月-2014年6月我院收治的80例高血压早期肾损害患者为研究对象，随机分为观察组40例与对照组40例；给予观察组患者活血利水中药复方联合硝苯地平控释片，对照组只给予西药治疗。治疗后对比两组治疗效果以及相关指标水平。结果：治疗后观察组的尿素氮、Cr、mALB、β2-MG水平均发生明显变化，并且与治疗前及对照组比较，其mALB、β2-MG水平差异显著，差异具有统计学意义，P<0.05。另外，观察组的治疗总有效率明显高于对照组，两组比较差异具有统计学意义，P<0.05。结论：相比于单纯使用活血利水中药复方，联合使用活血利水中药复方与西药治疗高血压早期肾损害的效果更好，且治疗后血压水平得到有效控制，肾功能得到有效改善。因此，该方法值得临床推广应用。
목적：탐토활혈이수중약복방연합서약대우고혈압조기신손해적림상료효。방법：선취2013년7월-2014년6월아원수치적80례고혈압조기신손해환자위연구대상，수궤분위관찰조40례여대조조40례；급여관찰조환자활혈이수중약복방연합초분지평공석편，대조조지급여서약치료。치료후대비량조치료효과이급상관지표수평。결과：치료후관찰조적뇨소담、Cr、mALB、β2-MG수평균발생명현변화，병차여치료전급대조조비교，기mALB、β2-MG수평차이현저，차이구유통계학의의，P<0.05。령외，관찰조적치료총유효솔명현고우대조조，량조비교차이구유통계학의의，P<0.05。결론：상비우단순사용활혈이수중약복방，연합사용활혈이수중약복방여서약치료고혈압조기신손해적효과경호，차치료후혈압수평득도유효공제，신공능득도유효개선。인차，해방법치득림상추엄응용。
Objective: To observe clinical efficacy of the Huoxue Lishui prescription plus western medicine on renal damage in early hypertension. Methods: 80 cases were divided into the observed group and control group, 40 cases for each group. The observed group was given the Huoxue Lishui prescription and Nifedipine GITS. The control group was given western medicine. Results: Compared with before treatment and the control group, usea nitrogen, Cr,mALB andβ2-MG significantly were changed in the observed group, with a statistically significant difference. The efficiency in the observe group was obviously better (P<0.05). Conclusion: The Huoxue Lishui prescription plus western medicine came to better efficacy, with effectively controlled blood pressure and improved renal function, and was worthy of promotion.