CAJ | 학술논문

目的：探讨膀胱癌术后的复发率及危险因素。方法选择158例膀胱癌手术患者，随访3年，依据是否发生复发将患者分为复发组和无复发组，收集可能影响术后复发的相关因素，采用单因素和多因素分析方法来筛选影响术后复发的危险因素。结果膀胱癌患者术后3年复发率为26.6％(42/158)；单因素分析显示肿瘤分级、肿瘤分期、肿瘤大小、肿瘤数量、手术方式、淋巴结转移、术后辅助化疗影响术后复发；而多因素分析结果显示，肿瘤分级(OR=2.632)、肿瘤分期(OR=2.690)、手术方式(OR=2.936)、淋巴结转移(OR=9.935)为术后复发的危险因素，而术后辅助化疗(OR=0.154)则为保护因素。结论膀胱癌术后复发的独立危险因素包括肌层浸润性膀胱癌、肿瘤分级和肿瘤分期越高、部分膀胱切除术、发生淋巴结转移、术后未进行化疗。
목적：탐토방광암술후적복발솔급위험인소。방법선택158례방광암수술환자，수방3년，의거시부발생복발장환자분위복발조화무복발조，수집가능영향술후복발적상관인소，채용단인소화다인소분석방법래사선영향술후복발적위험인소。결과방광암환자술후3년복발솔위26.6％(42/158)；단인소분석현시종류분급、종류분기、종류대소、종류수량、수술방식、림파결전이、술후보조화료영향술후복발；이다인소분석결과현시，종류분급(OR=2.632)、종류분기(OR=2.690)、수술방식(OR=2.936)、림파결전이(OR=9.935)위술후복발적위험인소，이술후보조화료(OR=0.154)칙위보호인소。결론방광암술후복발적독립위험인소포괄기층침윤성방광암、종류분급화종류분기월고、부분방광절제술、발생림파결전이、술후미진행화료。
Objective To explore the relapse rate and correlated risk factors of bladder carcinoma after operation. Methods One hundred and fifty-eight patients with bladder carcinoma operation were divided into relapse group and without-re-lapse group, through 3 years following-up. Correlated risk factors that could affect relapse after operation were collected, and risk factors were screened by single factor and multiple factors analysis methods. Results The relapse rate of bladder carcinoma after 3 years'operation was 26. 6 percent (42/158). Single factor analysis showed that the factors of tumor grading, tumor staging, tumor size, tumor amount, operation styles, lymphatic metastasis and adjuvant chemotherapy after operation affected the relapse of bladder carcinoma after operation. Multiple factors analysis results showed that the risk factors of bladder carcinoma after oper-ation included in tumor grading (OR=2. 632), tumor staging (OR=2. 690), operation styles (OR=2. 936) and lymphatic me-tastasis (OR=9. 935), but adjuvant chemotherapy after operation was the protective factor of bladder carcinoma after operation. Conclusion The independent risk factors of bladder carcinoma after operation include muscle invasive bladder cancer, higher tumor grading or staging of tumor, partial cystectomy, incidence of lymphatic metastasis and adjuvant chemotherapy after opera-tion.