中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2015年
37期
6017-6023
,共7页
刚嘉鸿%宓轶群%张永亮%王华敏
剛嘉鴻%宓軼群%張永亮%王華敏
강가홍%복질군%장영량%왕화민
组织构建%骨组织工程%膝关节骨性关节炎%非手术疗法%临床疗效评价%量表%生物力学%影像学%组织工程
組織構建%骨組織工程%膝關節骨性關節炎%非手術療法%臨床療效評價%量錶%生物力學%影像學%組織工程
조직구건%골조직공정%슬관절골성관절염%비수술요법%림상료효평개%량표%생물역학%영상학%조직공정
背景:非手术疗法治疗膝骨关节炎疗效确切,但是缺乏科学合理的疗效评价系统。目的:详细阐述近5年来非手术疗法治疗膝骨关节炎临床疗效评价方法。<br> 方法:查阅 PubMed、WOK、CNKI、维普、万方等相关数据库,查找关于膝骨关节炎非手术疗法临床疗效评价方法的文献,对资料进行初审,剔除无关文献,保留与非手术疗法治疗膝骨关节炎临床疗效评价方法相关的研究文献,排除重复研究及不典型报道。<br> 结果与结论:共纳入42篇符合标准文献,包括中文文献28篇,英文文献14篇。经分析得出:膝骨关节炎非手术疗法可以有效改善膝关节功能,提高患者生活质量,具有确切的疗效和较好的经济效益。因此探索科学、合理的临床疗效评价方法,用以指导最优临床疗法的选择,进一步提高非手术疗法治疗膝关节骨性关节炎的疗效和可推广性,具有重要意义。以量表为主的评价方法简便易行,具有可实践性,但是单一量表评价方法存在主观性较强等不足。生物力学、影像学检查等疗效评价方法客观、可信度高,且有准确、无创等优势。在疗效评价体系中,应该多引入主观量表观察与客观指标相结合的评价方式,根据不同侧重,选取相应的疗效评价方法。
揹景:非手術療法治療膝骨關節炎療效確切,但是缺乏科學閤理的療效評價繫統。目的:詳細闡述近5年來非手術療法治療膝骨關節炎臨床療效評價方法。<br> 方法:查閱 PubMed、WOK、CNKI、維普、萬方等相關數據庫,查找關于膝骨關節炎非手術療法臨床療效評價方法的文獻,對資料進行初審,剔除無關文獻,保留與非手術療法治療膝骨關節炎臨床療效評價方法相關的研究文獻,排除重複研究及不典型報道。<br> 結果與結論:共納入42篇符閤標準文獻,包括中文文獻28篇,英文文獻14篇。經分析得齣:膝骨關節炎非手術療法可以有效改善膝關節功能,提高患者生活質量,具有確切的療效和較好的經濟效益。因此探索科學、閤理的臨床療效評價方法,用以指導最優臨床療法的選擇,進一步提高非手術療法治療膝關節骨性關節炎的療效和可推廣性,具有重要意義。以量錶為主的評價方法簡便易行,具有可實踐性,但是單一量錶評價方法存在主觀性較彊等不足。生物力學、影像學檢查等療效評價方法客觀、可信度高,且有準確、無創等優勢。在療效評價體繫中,應該多引入主觀量錶觀察與客觀指標相結閤的評價方式,根據不同側重,選取相應的療效評價方法。
배경:비수술요법치료슬골관절염료효학절,단시결핍과학합리적료효평개계통。목적:상세천술근5년래비수술요법치료슬골관절염림상료효평개방법。<br> 방법:사열 PubMed、WOK、CNKI、유보、만방등상관수거고,사조관우슬골관절염비수술요법림상료효평개방법적문헌,대자료진행초심,척제무관문헌,보류여비수술요법치료슬골관절염림상료효평개방법상관적연구문헌,배제중복연구급불전형보도。<br> 결과여결론:공납입42편부합표준문헌,포괄중문문헌28편,영문문헌14편。경분석득출:슬골관절염비수술요법가이유효개선슬관절공능,제고환자생활질량,구유학절적료효화교호적경제효익。인차탐색과학、합리적림상료효평개방법,용이지도최우림상요법적선택,진일보제고비수술요법치료슬관절골성관절염적료효화가추엄성,구유중요의의。이량표위주적평개방법간편역행,구유가실천성,단시단일량표평개방법존재주관성교강등불족。생물역학、영상학검사등료효평개방법객관、가신도고,차유준학、무창등우세。재료효평개체계중,응해다인입주관량표관찰여객관지표상결합적평개방식,근거불동측중,선취상응적료효평개방법。
BACKGROUND:Studies have shown that the non-surgical therapy for knee osteoarthritis is exactly effective, but there is a lack of scientific and rational evaluation system. OBJECTIVE:To review the evaluation methods of non-surgical therapy for knee osteoarthritis in recent 5 years. METHODS:A computer-based retrieval of PubMed, WOK, CNKI, VIP, Wanfang databases was performed to find literature related to the evaluation methods of non-surgical therapy for knee osteoarthritis. Al data were primarily screened to exclude irrelevant literature. Those literatures about the evaluation methods of non-surgical therapy for knee osteoarthritis were included. Repetitive studies and untypical reports were excluded. RESULTS AND CONCLUSION:Total y 42 articles were col ected, including 28 in Chinese and 14 in English. The analysis results showed that the non-surgical treatment for knee osteoarthritis can improve knee function and the quality of life in patients, and have an exact effect and a good economic benefit. Therefore, exploring a scientific and reasonable evaluation method to guide the choice of clinical treatment for knee osteoarthritis is greatly significant, which can improve the efficacy of non-surgical therapy for knee osteoarthritis. Scale-based evaluation method is simple and practical, but the presence of a single scale has a lack of objectivity. The method of biomechanics or imaging has the advantages of objective, highly reliable, accurate, non-invasive and so on. In the future therapeutic evaluation system, the combination of subjective scale observation and objective indicators should be more recommended, and the evaluation methods of non-surgical therapy for knee osteoarthritis should be selected appropriately based on the difference of clinical therapy and effect.