CAJ | 학술논문

目的：探讨冠状动脉慢血流（CSF）患者的颈动脉弹性参数与血浆同型半胱氨酸（HCY）浓度的相关性。方法选取确诊为CSF的患者108例作为CSF组，同期经冠状动脉造影证实无狭窄的健康人群105例作为对照组，两组分别采用血管回声跟踪（ET）技术检测弹性指数（β）、压力‐应变弹性指数（Ep）、顺应性（AC）和脉搏波传递速度（PWV ）等动脉弹性参数，同时进行 HCY浓度测定。结果 CSF组超声检测的颈动脉弹性参数β、Ep、PWV与对照组比较明显升高，而AC明显降低，差异均有统计学意义（P＜0．01）。CSF组 HCY浓度较对照组明显升高，差异有统计学意义（P＜0．05）。CSF组HCY浓度与颈动脉弹性参数β、Ep和PWV呈正相关，与AC呈负相关。结论 ET技术是评价CSF患者颈动脉弹性的简单、实用方法，CSF患者 HCY浓度与颈动脉弹性参数具有良好的相关性。
목적：탐토관상동맥만혈류（CSF）환자적경동맥탄성삼수여혈장동형반광안산（HCY）농도적상관성。방법선취학진위CSF적환자108례작위CSF조，동기경관상동맥조영증실무협착적건강인군105례작위대조조，량조분별채용혈관회성근종（ET）기술검측탄성지수（β）、압력‐응변탄성지수（Ep）、순응성（AC）화맥박파전체속도（PWV ）등동맥탄성삼수，동시진행 HCY농도측정。결과 CSF조초성검측적경동맥탄성삼수β、Ep、PWV여대조조비교명현승고，이AC명현강저，차이균유통계학의의（P＜0．01）。CSF조 HCY농도교대조조명현승고，차이유통계학의의（P＜0．05）。CSF조HCY농도여경동맥탄성삼수β、Ep화PWV정정상관，여AC정부상관。결론 ET기술시평개CSF환자경동맥탄성적간단、실용방법，CSF환자 HCY농도여경동맥탄성삼수구유량호적상관성。
Objective To investigate the relationship between the carotid artery elasticity parameters and plas‐ma homocysteine in the patients with coronary slow flow (CSF) .Methods 108 patients with CSF were selected as the CSF group ,meanwhile ,105 healthy individuals without stenosis verified by coronary arteriography were taken as the control group .The echo tracking(ET) technique was adopted to detect the arterial elastic parameters of the elastic in‐dex(β) ,pressure‐strain elastic modulus(Ep) ,arterial compliance(AC) and local pulse wave velocity (PWV) .Mean‐while ,the level of plasma homocysteine(HCY) was measured in the two groups .Results The stiffness parameters ofβ,Ep and PWV in the CSF group were significantly higher than those in the control group ,while AC was significantly decreased compared with the control group ,the differences were statistically significant (P<0 .01) .The level of plas‐ma HCY level in the CSF group was significantly increased compared with the control group ,the difference was sta‐tistically significant(P<0 .05) .The level of HCY in the CSF group was positively correlated with β,Ep and PWV , but negatively correlated with AC .Conclusion ET technique is a simple practical method to evaluate carotid artery e‐lasticity in the patients with CSF .The plasma HCY level has good correlation with the carotid artery elasticity pa‐rameters in the CSF patients .