中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
26期
116-118,121
,共4页
老年性聋%神经生长因子%耳后注射%治疗效果%临床价值
老年性聾%神經生長因子%耳後註射%治療效果%臨床價值
노년성롱%신경생장인자%이후주사%치료효과%림상개치
Presbycusis%Nerve growth factors%Postaurical injection%Therapy effect%Clinical value
目的：探究老年性聋采用耳后注射神经生长因子治疗的效果和临床价值。方法选取我院于2014年8月~2015年4月收治的老年性聋患者64例，采用数字法将患者分为对照组和观察组，各组32例，对照组患者采用葛根素氯化钠静脉滴注治疗，观察组患者采用神经生长因子耳后注射治疗，治疗后观察比较两组患者临床症状消失时间、治疗效果、患者情绪状况(SAS、SDS评分)及并发症发生情况。结果治疗后观察组患者临床症状消失时间短于对照组(P<0.05)；观察组患者治疗总有效率为46.9%，对照组患者治疗总有效率为25.0%，两组患者治疗总有效率比较，差异有统计学意义(P<0.05)；对照组和观察组患者SAS、SDS评分均显著低于治疗前(P<0.05)，且观察组患者SAS、SDS评分下降程度均优于对照组(P<0.05)。治疗后两组患者均未出现任何严重性并发症，对整体治疗效果影响不大。结论耳后注射神经生长因子治疗老年性聋，能有效缓解或改善患者临床症状，促进患者听力快速恢复，改善患者心理状况，消除负面情绪，且治疗后患者并发症较少，治疗效果良好，值得临床推广应用。
目的：探究老年性聾採用耳後註射神經生長因子治療的效果和臨床價值。方法選取我院于2014年8月~2015年4月收治的老年性聾患者64例，採用數字法將患者分為對照組和觀察組，各組32例，對照組患者採用葛根素氯化鈉靜脈滴註治療，觀察組患者採用神經生長因子耳後註射治療，治療後觀察比較兩組患者臨床癥狀消失時間、治療效果、患者情緒狀況(SAS、SDS評分)及併髮癥髮生情況。結果治療後觀察組患者臨床癥狀消失時間短于對照組(P<0.05)；觀察組患者治療總有效率為46.9%，對照組患者治療總有效率為25.0%，兩組患者治療總有效率比較，差異有統計學意義(P<0.05)；對照組和觀察組患者SAS、SDS評分均顯著低于治療前(P<0.05)，且觀察組患者SAS、SDS評分下降程度均優于對照組(P<0.05)。治療後兩組患者均未齣現任何嚴重性併髮癥，對整體治療效果影響不大。結論耳後註射神經生長因子治療老年性聾，能有效緩解或改善患者臨床癥狀，促進患者聽力快速恢複，改善患者心理狀況，消除負麵情緒，且治療後患者併髮癥較少，治療效果良好，值得臨床推廣應用。
목적：탐구노년성롱채용이후주사신경생장인자치료적효과화림상개치。방법선취아원우2014년8월~2015년4월수치적노년성롱환자64례，채용수자법장환자분위대조조화관찰조，각조32례，대조조환자채용갈근소록화납정맥적주치료，관찰조환자채용신경생장인자이후주사치료，치료후관찰비교량조환자림상증상소실시간、치료효과、환자정서상황(SAS、SDS평분)급병발증발생정황。결과치료후관찰조환자림상증상소실시간단우대조조(P<0.05)；관찰조환자치료총유효솔위46.9%，대조조환자치료총유효솔위25.0%，량조환자치료총유효솔비교，차이유통계학의의(P<0.05)；대조조화관찰조환자SAS、SDS평분균현저저우치료전(P<0.05)，차관찰조환자SAS、SDS평분하강정도균우우대조조(P<0.05)。치료후량조환자균미출현임하엄중성병발증，대정체치료효과영향불대。결론이후주사신경생장인자치료노년성롱，능유효완해혹개선환자림상증상，촉진환자은력쾌속회복，개선환자심리상황，소제부면정서，차치료후환자병발증교소，치료효과량호，치득림상추엄응용。
Objective To explore the therapy effect and clinical value of postaurical injection nerve growth factors (NGF) in treatment presbycusis. Methods 64 presbycusis patients from August 2014 to April 2015 of our hospital were selected.Patients were divided into control group (n=32) and observation group (n=32) by using digital method.Patients in control group were given intravenous administration Pue rarin sodium chloride,and patients in observation group were given postaurical injection NGF.The time of clinical symptoms disappeared,therapy effect,patients’emotional state (SAS score and SDS score) and occurrence of complications were observed and compared between two groups after treatment. Results After treatment,the time of clinical symptoms disappeared was shorter in observation group than control group,with statistical difference(P<0.05).The total effective rate was 46.9%in observation group and was 25.0%in control group,with statistical difference (P<0.05).The scores of SAS and SDS decreased compared with prior treatment between two groups (P<0.05),and the scores in observation group decreased more than control group,with statistical difference(P<0.05).There was no serious complications appeared between two groups and had little influence on the overall treatment effect. Conclusion Using postaurical injection nerve growth factors in treatment presbycusis can effectively relieve or improve patients’ clinical symptoms,accelerate the recovery of patients’ hearing,improve patients’ psychological status,eliminate negative emotions and has less complications and good outcomesafter treatment.It is worth popularizing in clinical.
