临床肺科杂志
臨床肺科雜誌
림상폐과잡지
Journal of Clinical Pulmonary Medicine
2015年
11期
2046-2049
,共4页
支气管肺发育不良%早产儿%诊断%治疗
支氣管肺髮育不良%早產兒%診斷%治療
지기관폐발육불량%조산인%진단%치료
bronchopulmonary dysplasia%premature infant%diagnosis%treatment
目的：分析早产儿支气管肺发育不良( Bronchopulmonary dysplasia,BPD)的临床特点,为早产儿BPD的防治提供依据。方法对52例BPD患儿进行回顾性分析,总结患儿出生时、母孕期以及其合并症、治疗等的一般情况。结果284例极低出生体重儿中52例发生BPD,其中胎龄≤28周7例,28周<胎龄≤32周38例,32周<胎龄≤34周7例。出生体重BW<1000 g 6例,1000 g≤BW<1500 g 32例。轻度BPD 35例(67．3%),中度9例(17．3%),重度8例(15．4%)。29例(55．8%)患儿母亲有妊娠合并症,其中13例(25%)合并有妊娠高血压,12例(23%)有胎膜早破。经综合治疗后,52例BPD患儿中有3例放弃治疗,3例因长期不能脱氧而建议转上级医院继续治疗,其余均好转出院。结论早产、极低出生体重儿、机械通气、感染、动脉导管未闭等是BPD发生的重要因素,另外,高龄产妇及母孕期的合并症、以及胎儿的性别也影响BPD的发生。所以对易感患儿进行严密监测、早期诊断、防治感染、及时关闭导管、应用利尿剂和激素是预防和治疗BPD的重要措施。
目的：分析早產兒支氣管肺髮育不良( Bronchopulmonary dysplasia,BPD)的臨床特點,為早產兒BPD的防治提供依據。方法對52例BPD患兒進行迴顧性分析,總結患兒齣生時、母孕期以及其閤併癥、治療等的一般情況。結果284例極低齣生體重兒中52例髮生BPD,其中胎齡≤28週7例,28週<胎齡≤32週38例,32週<胎齡≤34週7例。齣生體重BW<1000 g 6例,1000 g≤BW<1500 g 32例。輕度BPD 35例(67．3%),中度9例(17．3%),重度8例(15．4%)。29例(55．8%)患兒母親有妊娠閤併癥,其中13例(25%)閤併有妊娠高血壓,12例(23%)有胎膜早破。經綜閤治療後,52例BPD患兒中有3例放棄治療,3例因長期不能脫氧而建議轉上級醫院繼續治療,其餘均好轉齣院。結論早產、極低齣生體重兒、機械通氣、感染、動脈導管未閉等是BPD髮生的重要因素,另外,高齡產婦及母孕期的閤併癥、以及胎兒的性彆也影響BPD的髮生。所以對易感患兒進行嚴密鑑測、早期診斷、防治感染、及時關閉導管、應用利尿劑和激素是預防和治療BPD的重要措施。
목적：분석조산인지기관폐발육불량( Bronchopulmonary dysplasia,BPD)적림상특점,위조산인BPD적방치제공의거。방법대52례BPD환인진행회고성분석,총결환인출생시、모잉기이급기합병증、치료등적일반정황。결과284례겁저출생체중인중52례발생BPD,기중태령≤28주7례,28주<태령≤32주38례,32주<태령≤34주7례。출생체중BW<1000 g 6례,1000 g≤BW<1500 g 32례。경도BPD 35례(67．3%),중도9례(17．3%),중도8례(15．4%)。29례(55．8%)환인모친유임신합병증,기중13례(25%)합병유임신고혈압,12례(23%)유태막조파。경종합치료후,52례BPD환인중유3례방기치료,3례인장기불능탈양이건의전상급의원계속치료,기여균호전출원。결론조산、겁저출생체중인、궤계통기、감염、동맥도관미폐등시BPD발생적중요인소,령외,고령산부급모잉기적합병증、이급태인적성별야영향BPD적발생。소이대역감환인진행엄밀감측、조기진단、방치감염、급시관폐도관、응용이뇨제화격소시예방화치료BPD적중요조시。
Objective To analyze the clinical features of premature infants with bronchopulmonary dysplasia ( BPD) . Methods The clinical data of 52 premature infants with BPD were retrospectively analyzed to summarize the history of birth and mother pregnancy, clinical treatment, and complications. Results There were 52 cases of BPD among the total of 284 cases of very low birth weight, including 7 cases of gestation age less than 28 weeks, 38 cases between 28 weeks and 32 weeks, and 7 cases between 32 weeks and 34 weeks. The birth weight less than 1000g included 6 cases, and 32 cases between 1000g and 1500g. Of the 52 premature neonates, 35 cases were diag-nosed as mild BPD, 9 cases as moderate BPD, and 8 cases as severe BPD. There were 29 mothers with pregnancy complications, which were 13 cases with hypertensive disorders in pregnancy and 12 cases with premature rupture of membrane. After the comprehensive treatment, 3 cases gave up treatment, 3 cases suggested the superior hospital continue to treatment, and 46 cases recovered after treatment and discharged. Conclusion The risk factors of BPD include premature birth, very low birth weight, mechanical ventilation, infection, and patent ductus arteriosus. Be-sides, elderly puerperant, pregnancy complication and sexuality also affect the incidence of BPD. The important measures for BPD are close monitoring, early diagnosis, infection prevention, timely ductus closure, and early appli-cation of diuretics and glucocorticoid.
