CAJ | 학술논문

目的：探讨内镜下经鼻蝶入路二次手术治疗复发垂体瘤患者的临床有效性及安全性，并总结手术操作技巧。方法选取2008-03～2014-02在兰州市第一人民医院脑外科住院的垂体瘤复发患者245例，患者初次垂体瘤手术方式为经蝶入路或开颅手术，后给予其二次内镜下经鼻蝶手术治疗，观察患者瘤体切除程度、术后视力及内分泌变化及并发症的发生情况，分析二次经蝶入路手术治疗垂体瘤的有效性及安全性。结果内镜下经鼻蝶入路二次手术治疗垂体瘤全切加次全切除率达80.38％，无严重并发症发生，无死亡病例。结论内镜下经鼻蝶入路二次手术治疗复发垂体瘤安全有效，值得临床推广应用。
목적：탐토내경하경비접입로이차수술치료복발수체류환자적림상유효성급안전성，병총결수술조작기교。방법선취2008-03～2014-02재란주시제일인민의원뇌외과주원적수체류복발환자245례，환자초차수체류수술방식위경접입로혹개로수술，후급여기이차내경하경비접수술치료，관찰환자류체절제정도、술후시력급내분비변화급병발증적발생정황，분석이차경접입로수술치료수체류적유효성급안전성。결과내경하경비접입로이차수술치료수체류전절가차전절제솔체80.38％，무엄중병발증발생，무사망병례。결론내경하경비접입로이차수술치료복발수체류안전유효，치득림상추엄응용。
Objective To investigate the effectiveness and safety of the endoscopic transnasal transsphenoi-dal method and endoscopic transsphenoidal surgery for the treatment of craniotomy or microscopic tumor with relapsed after resection of pituitary.Methods Two hundred and forty-five patients with pituitary tumor recurrence were col-lected from March 2008 to February 2014,who were performed by transsphenoidal or craniotomy for the first opera-tion.All the patients were included in this study and were given secondary endoscopic transsphenoidal surgery.Tumor resection extent,endocrine changes in visual acuity and complications were analyzed.Results The surgery subtotal resection rate was 80.38%,without dead cases and serious complications.Conclusion Endoscopic transsphenoidal resection of pituitary tumors is safe and effective.