CAJ | 학술논문

目的：探讨阿托品联合奥美拉唑治疗急性胃炎的临床疗效。方法以该院收治的100例急性胃炎患者为研究对象，根据临床治疗方式的不同分为对照组与观察组，每组50例。对照组采用山莨菪碱联合奥美拉唑治疗，观察组采用阿托品联合奥美拉唑治疗。两组均治疗2周。在治疗结束后对比两组患者的临床疗效。结果观察组显效38例，有效11例，无效1例。对照组显效28例，有效15例，无效7例。观察组疗效优于对照组（Z＝4.84，P＜0.05）；观察组不良反应发生率为8.0％，明显低于对照组的24.0％（P＜0.05）。观察组首次用药后显效率为76.0％，高于对照组的44.0％（ P＜0.05）。结论阿托品联合奥美拉唑治疗急性胃炎的临床疗效显著，能够快速缓解急性胃炎患者的疼痛症状，且治疗安全性高，不良反应少。
목적：탐토아탁품연합오미랍서치료급성위염적림상료효。방법이해원수치적100례급성위염환자위연구대상，근거림상치료방식적불동분위대조조여관찰조，매조50례。대조조채용산랑탕감연합오미랍서치료，관찰조채용아탁품연합오미랍서치료。량조균치료2주。재치료결속후대비량조환자적림상료효。결과관찰조현효38례，유효11례，무효1례。대조조현효28례，유효15례，무효7례。관찰조료효우우대조조（Z＝4.84，P＜0.05）；관찰조불량반응발생솔위8.0％，명현저우대조조적24.0％（P＜0.05）。관찰조수차용약후현효솔위76.0％，고우대조조적44.0％（ P＜0.05）。결론아탁품연합오미랍서치료급성위염적림상료효현저，능구쾌속완해급성위염환자적동통증상，차치료안전성고，불량반응소。
Objective To investigate the clinical efficacy of atropine combined with omeprazole in the treat-ment of patients with acute gastritis.Methods One hundred patients with acute gastritis were divided into the control group(n=50) and the observation group(n=50).The control group was treated with anisodamine combined with omeprazole, and the observation group was treated with atropine combined with omeprazole.The clinical efficacy was compared between the two groups.Results The effective rate of the observation group was significantly higher than that of the control group(P<0.05).The incidence of adverse reactions was obviously lower in the observation group than that in the control group(P<0.05).The rate of significant efficiency for the first time after the medication in the observation group(76.0%) was significantly higher than that in the control group(44.0%)(P<0.05).Conclu-sion Atropine combined with omeprazole is safe and effective in the treatment of acute gastritis, which quickly re-duces the symptom of pain and improves the patients′quality of life.