中国医药导报
中國醫藥導報
중국의약도보
China Medical Herald
2015年
27期
109-111,115
,共4页
磷酸肌酸钠%维生素C%病毒性心肌炎%心肌酶%肌钙蛋白I
燐痠肌痠鈉%維生素C%病毒性心肌炎%心肌酶%肌鈣蛋白I
린산기산납%유생소C%병독성심기염%심기매%기개단백I
Creatine phosphate sodium%Vitamin C%Viral myocarditis%Myocardial enzyme%Troponin I
目的：研究磷酸肌酸钠联合维生素C治疗小儿病毒性心肌炎的临床效果以及其对心肌酶和肌钙蛋白I的影响。方法选取2013年1月~2014年7月深圳市人民医院收治的小儿病毒性心肌炎患者120例,按照随机数字表法将患儿分为研究组和对照组,每组60例。对照组给予常规治疗,研究组在常规治疗基础上给予磷酸肌酸钠联合维生素C治疗。比较两组临床疗效、心电图、心肌酶、肌钙蛋白I和不良反应。结果研究组总有效率为86.7%(52/60),显著高于对照组(71.7%,43/60),差异有统计学意义(P<0.05)；研究组心电图总有效率为73.3%(44/60),显著高于对照组(33.3%,20/60),差异有统计学意义(P<0.05)；治疗后研究组心肌酶和肌钙蛋白I均显著改善,与治疗前比较差异有统计学意义(P<0.05),与对照组比较差异有统计学意义(P<0.05)；两组均无严重不良反应。结论磷酸肌酸钠联合维生素C治疗小儿病毒性心肌炎具有较好的临床效果,能显著改善心肌酶和肌钙蛋白I的水平。
目的：研究燐痠肌痠鈉聯閤維生素C治療小兒病毒性心肌炎的臨床效果以及其對心肌酶和肌鈣蛋白I的影響。方法選取2013年1月~2014年7月深圳市人民醫院收治的小兒病毒性心肌炎患者120例,按照隨機數字錶法將患兒分為研究組和對照組,每組60例。對照組給予常規治療,研究組在常規治療基礎上給予燐痠肌痠鈉聯閤維生素C治療。比較兩組臨床療效、心電圖、心肌酶、肌鈣蛋白I和不良反應。結果研究組總有效率為86.7%(52/60),顯著高于對照組(71.7%,43/60),差異有統計學意義(P<0.05)；研究組心電圖總有效率為73.3%(44/60),顯著高于對照組(33.3%,20/60),差異有統計學意義(P<0.05)；治療後研究組心肌酶和肌鈣蛋白I均顯著改善,與治療前比較差異有統計學意義(P<0.05),與對照組比較差異有統計學意義(P<0.05)；兩組均無嚴重不良反應。結論燐痠肌痠鈉聯閤維生素C治療小兒病毒性心肌炎具有較好的臨床效果,能顯著改善心肌酶和肌鈣蛋白I的水平。
목적：연구린산기산납연합유생소C치료소인병독성심기염적림상효과이급기대심기매화기개단백I적영향。방법선취2013년1월~2014년7월심수시인민의원수치적소인병독성심기염환자120례,안조수궤수자표법장환인분위연구조화대조조,매조60례。대조조급여상규치료,연구조재상규치료기출상급여린산기산납연합유생소C치료。비교량조림상료효、심전도、심기매、기개단백I화불량반응。결과연구조총유효솔위86.7%(52/60),현저고우대조조(71.7%,43/60),차이유통계학의의(P<0.05)；연구조심전도총유효솔위73.3%(44/60),현저고우대조조(33.3%,20/60),차이유통계학의의(P<0.05)；치료후연구조심기매화기개단백I균현저개선,여치료전비교차이유통계학의의(P<0.05),여대조조비교차이유통계학의의(P<0.05)；량조균무엄중불량반응。결론린산기산납연합유생소C치료소인병독성심기염구유교호적림상효과,능현저개선심기매화기개단백I적수평。
Objective To study the clinical effect of creatine phosphate sodium combined with vitamin C in treatment of children with viral myocarditis and its influence on myocardial enzymes and cardiac troponin I. Methods 120 cases of children with viral myocarditis from January 2013 to July 2014 in Shenzhen People's Hospital were selected, they were divided into study group and control group according to the random number table methods, with 60 cases in each group. The control group was given routine treatment, while the study group received the creatine phosphate sodium combined with vitamin C for treatment on the basis of the control group. Clinical curative effect, ECG, myocardial en-zyme, troponin I and adverse reaction of the two groups were compared. Results The total effective rate of the study group was 86.7%(52/60), significantly higher than 71.7%(43/60) of the control group, with statistical significant differ-ence between the two groups (P<0.05); total effective rate of ECG in the study group was 73.3% (44/60), significantly higher than 33.3% (20/60) of the control group, the difference of the two groups was statistically significant (P< 0.05);after the treatment, the myocardial enzyme and troponin I of the study group were significantly improved, when com-pared with before treatment the difference was statistically significant (P< 0.05), so as with the control group (P<0.05); there was no serious adverse reaction in both two groups. Conclusion Creatine phosphate sodium combined with vitamin C have good curative effect in treatment of viral myocarditis in children, which can significantly improve the level of myocardial enzymes and cardiac troponin I.
