临床药物治疗杂志
臨床藥物治療雜誌
림상약물치료잡지
Clinical Medication Journal
2015年
5期
62-65
,共4页
恶性综合征%抗精神病药%对症治疗
噁性綜閤徵%抗精神病藥%對癥治療
악성종합정%항정신병약%대증치료
neuroleptic malignant syndrome%antipsychotics%symptomatic treatment
目的：笔者主要是通过收集抗精神病药物使用后出现恶性综合征的病历，并对该不良反应做出处理和分析。探讨恶性综合征的诱发因素及发病特征，为临床合理用药提供参考。方法：跟踪我院精神科住院患者出现恶性综合征的2例病历，分析恶性综合征的发病原因，发病过程，制定给药方案。结果：通过合理治疗，两例患者均能康复出院。结论：恶性综合征是一种与抗精神病药物治疗有关的严重并发症，治疗的关键就在于早期发现、立即停用抗精神病药物，及时对症治疗，支持治疗，加强护理。
目的：筆者主要是通過收集抗精神病藥物使用後齣現噁性綜閤徵的病歷，併對該不良反應做齣處理和分析。探討噁性綜閤徵的誘髮因素及髮病特徵，為臨床閤理用藥提供參攷。方法：跟蹤我院精神科住院患者齣現噁性綜閤徵的2例病歷，分析噁性綜閤徵的髮病原因，髮病過程，製定給藥方案。結果：通過閤理治療，兩例患者均能康複齣院。結論：噁性綜閤徵是一種與抗精神病藥物治療有關的嚴重併髮癥，治療的關鍵就在于早期髮現、立即停用抗精神病藥物，及時對癥治療，支持治療，加彊護理。
목적：필자주요시통과수집항정신병약물사용후출현악성종합정적병력，병대해불량반응주출처리화분석。탐토악성종합정적유발인소급발병특정，위림상합리용약제공삼고。방법：근종아원정신과주원환자출현악성종합정적2례병력，분석악성종합정적발병원인，발병과정，제정급약방안。결과：통과합리치료，량례환자균능강복출원。결론：악성종합정시일충여항정신병약물치료유관적엄중병발증，치료적관건취재우조기발현、립즉정용항정신병약물，급시대증치료，지지치료，가강호리。
Objective: Cases with Neuroleptic malignant syndrome (NMS) caused by antipsychotics were collected - and the adverse reactions were analyzed. To explore the predisposing factors and clinical features of NMS and provide reference for clinical rational drug use.Method: By tracking patients medical records in our psychiatric department, two cases of NMS were enrolled and treated, . We analyzed the causes, pathogenesis, dosing regimens.Results: With proper treatment, two patients can discharged.Conclusion:Malignant syndrome is a rare, life-threatening adverse reaction to antipsychotic medication.The key of the treatment for NMS lies on early detection, immediately discontinuing antipsychotics medication, timely symptomatic treatment, supportive therapy, and intensive care.
