CAJ | 학술논문

目的：探讨袖状肺叶切除术治疗老年中央型肺癌的可行性。方法选取本院2011年1月~2012年1月收治的老年中央型肺癌患者50例同时选取非老年患者50例进行研究,所有患者均采用袖状肺叶切除术治疗,观察两组患者治疗后3年生存率、术后肺功能改善以及术后并发症发生情况。结果两组患者术后用力肺活量(FVC)、1 s 用力呼气容积(FEV1)和FEV1/FVC 均较治疗前下降,差异有统计学意义,P<0．05,但组间比较无显著性差异,P>0．05；两组患者术后均未发生支气管瘘、狭窄及死亡等严重不良反应,老年组术后近期发生肺不张2例,发生率为4．0%,非老年组肺不张1例,发生率2．0%,两组相比,P>0．05；老年组3年后生存率为68．0%(34/50),非老年组3年后生存率为70．00%(35/70),两组相比,P>0．05。结论支气管袖状肺叶切除对老年中央型肺癌患者安全可行,术后并发症少,生存率较高,且可最大限度地保留患者肺功能,提高患者生活质量,值得进一步推广和研究。
목적：탐토수상폐협절제술치료노년중앙형폐암적가행성。방법선취본원2011년1월~2012년1월수치적노년중앙형폐암환자50례동시선취비노년환자50례진행연구,소유환자균채용수상폐협절제술치료,관찰량조환자치료후3년생존솔、술후폐공능개선이급술후병발증발생정황。결과량조환자술후용력폐활량(FVC)、1 s 용력호기용적(FEV1)화FEV1/FVC 균교치료전하강,차이유통계학의의,P<0．05,단조간비교무현저성차이,P>0．05；량조환자술후균미발생지기관루、협착급사망등엄중불량반응,노년조술후근기발생폐불장2례,발생솔위4．0%,비노년조폐불장1례,발생솔2．0%,량조상비,P>0．05；노년조3년후생존솔위68．0%(34/50),비노년조3년후생존솔위70．00%(35/70),량조상비,P>0．05。결론지기관수상폐협절제대노년중앙형폐암환자안전가행,술후병발증소,생존솔교고,차가최대한도지보류환자폐공능,제고환자생활질량,치득진일보추엄화연구。
Objective To investigate the feasibility of sleeve lobectomy for elderly patients with central lung canc-er. Methods 50 elderly patients with central lung cancer were selected as the observation group from January 2011 to Jan-uary 2012, and 50 non-elderly patients with central lung cancer were taken as the control group. All patients were treated with sleeve lobectomy and followed-up for 3 years. Their survival rate, lung function and postoperative complications were observed. Results The value of FVC, FEV1 and FEV1/FVC declined obviously in the two groups after the treatment ( P<0. 05), but there was no significant difference between the two groups (P>0. 05). There was no serious adverse reac-tions in the two groups, such as bronchial fistula, stenosis and death. The incidence of pulmonary atelectasis was 4. 0% in the observation group (2 cases), and 2. 0% in the control group (1 case) (P >0. 05). The 3-year survival rate was 68. 0% (34/50) in the observation group, and 70. 00% (35/70) in the control group (P>0. 05). Conclusion Bron-chial sleeve lobectomy is a feasible and safe method for elderly patients with central lung cancer, which has the advantages of less complications and higher survival rates, and can maximize the retention of lung function and improve the quality of life.