中国体外循环杂志
中國體外循環雜誌
중국체외순배잡지
Chinese Journal of Extracorporeal Circulation
2015年
3期
141-145
,共5页
丁晓晨%江春景%杨峰%郝星%邢智辰%徐博%江瑜%杨晓芳%杜中涛%邢家林%侯晓彤
丁曉晨%江春景%楊峰%郝星%邢智辰%徐博%江瑜%楊曉芳%杜中濤%邢傢林%侯曉彤
정효신%강춘경%양봉%학성%형지신%서박%강유%양효방%두중도%형가림%후효동
体外膜肺氧合%老年%冠状动脉旁路移植术%难治性心源性休克
體外膜肺氧閤%老年%冠狀動脈徬路移植術%難治性心源性休剋
체외막폐양합%노년%관상동맥방로이식술%난치성심원성휴극
Extracorporeal membrane oxygenation%Elderly%Coronary artery bypass grafting%Refractory postoperative cardio-genic shock
目的:回顾老年冠状动脉旁路移植( CABG)术后难治性心源性休克患者的体外膜肺氧合( ECMO)辅助情况,分析死亡率及可能影响辅助结果的相关危险因素。方法回顾本中心2011年1月至2014年12月共119例CABG术后出现难治性心源性低心排或术中难以脱离体外循环行ECMO辅助的患者,统计老年(年龄≥65岁)与非老年患者(年龄<65岁)的ECMO辅助结果并分析可能的相关危险因素。结果老年患者42例,平均年龄(69.4±3.5)岁,20例成功脱离ECMO(47.6%),10例存活出院(23.8%);非老年患者77例,平均年龄(55.1±6.6)岁,41例成功脱离ECMO(53.2%),其中33例存活出院(42.9%)。老年患者与非老年患者在下肢缺血(21.4% vs 6.5%)、肾功能不全(42.9% vs 16.9%)及透析应用(31.0% vs 13.0%)存在统计学差异( P<0.05)。 Logistic 回归分析发现肾功能不全和下肢缺血是影响CABG术后患者ECMO辅助结果的独立危险因素。结论对于CABG术后难治性心源性休克的老年冠心病患者,ECMO是一种有效的辅助治疗措施;下肢缺血、肾功能不全是影响ECMO辅助结果的独立危险因素。
目的:迴顧老年冠狀動脈徬路移植( CABG)術後難治性心源性休剋患者的體外膜肺氧閤( ECMO)輔助情況,分析死亡率及可能影響輔助結果的相關危險因素。方法迴顧本中心2011年1月至2014年12月共119例CABG術後齣現難治性心源性低心排或術中難以脫離體外循環行ECMO輔助的患者,統計老年(年齡≥65歲)與非老年患者(年齡<65歲)的ECMO輔助結果併分析可能的相關危險因素。結果老年患者42例,平均年齡(69.4±3.5)歲,20例成功脫離ECMO(47.6%),10例存活齣院(23.8%);非老年患者77例,平均年齡(55.1±6.6)歲,41例成功脫離ECMO(53.2%),其中33例存活齣院(42.9%)。老年患者與非老年患者在下肢缺血(21.4% vs 6.5%)、腎功能不全(42.9% vs 16.9%)及透析應用(31.0% vs 13.0%)存在統計學差異( P<0.05)。 Logistic 迴歸分析髮現腎功能不全和下肢缺血是影響CABG術後患者ECMO輔助結果的獨立危險因素。結論對于CABG術後難治性心源性休剋的老年冠心病患者,ECMO是一種有效的輔助治療措施;下肢缺血、腎功能不全是影響ECMO輔助結果的獨立危險因素。
목적:회고노년관상동맥방로이식( CABG)술후난치성심원성휴극환자적체외막폐양합( ECMO)보조정황,분석사망솔급가능영향보조결과적상관위험인소。방법회고본중심2011년1월지2014년12월공119례CABG술후출현난치성심원성저심배혹술중난이탈리체외순배행ECMO보조적환자,통계노년(년령≥65세)여비노년환자(년령<65세)적ECMO보조결과병분석가능적상관위험인소。결과노년환자42례,평균년령(69.4±3.5)세,20례성공탈리ECMO(47.6%),10례존활출원(23.8%);비노년환자77례,평균년령(55.1±6.6)세,41례성공탈리ECMO(53.2%),기중33례존활출원(42.9%)。노년환자여비노년환자재하지결혈(21.4% vs 6.5%)、신공능불전(42.9% vs 16.9%)급투석응용(31.0% vs 13.0%)존재통계학차이( P<0.05)。 Logistic 회귀분석발현신공능불전화하지결혈시영향CABG술후환자ECMO보조결과적독립위험인소。결론대우CABG술후난치성심원성휴극적노년관심병환자,ECMO시일충유효적보조치료조시;하지결혈、신공능불전시영향ECMO보조결과적독립위험인소。
Objective o retrospectively study the outcome of extracorporeal membrane oxygenation (ECMO) in elderly pa?tients with refractory postoperative cardiogenic shock ( PCS) after coronary artery bypass grafting ( CABG) from our center, and to ana?lyze the possible risk factors. Methods A total of 119 consecutive patients treated with ECMO because of PCS after CABG or unsuc?cess fully weaning from cardiopulmonary bypass ( CPB) during surgery from January 2011 to December 2014 were reviewed. Logistic a?nalysis was performed to identify the risk factors of the clinical outcome. Results There were 42 elderly patients (>=65years) with a mean age of 69.4±3.5 years. Twenty cases (47.6%) success fully weaned from ECMO and ten cases (23.8%) were discharged from hospital. There were 77 non-elderly patients (<65 years) with a mean age of 55.1±6.6 years. Forty-one (53.2%) cases success fully weaned from ECMO and 33 (42.9%) cases were discharged from hospital. Between the elderly and non-elderly patients, significant difference was noted in lower limb ischemia (21.4% vs 6.5%), renal failure (42.9% vs 16.9%) and the frequency of dialysis (31.0%vs 13.0%) . Logistic analysis found that renal failure and lower limb ischemia wereindependent risk factors associated with theclinical outcome of patients. Conclusions ECMO is an effective treatment for eldely patients with PCS after CABG; Renal failure and lower limb ischemia are indepedent risk factors of the outcome of ECMO support.