中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
27期
96-98
,共3页
幽门螺杆菌%Hp根除%胃铋镁颗粒%四联疗法
幽門螺桿菌%Hp根除%胃鉍鎂顆粒%四聯療法
유문라간균%Hp근제%위필미과립%사련요법
Helicobacter pylori%Hp eradication%Bismuth magnesium granule%Quadruple therapy
目的：观察含胃铋镁四联疗法根除幽门螺杆菌（Hp）的临床疗效。方法选择2014年10月~2015年3月孝感市中心医院经13C-尿素呼气试验确诊的96例Hp感染患者为研究对象，随机分为治疗组和对照组，各48例。治疗组给予含胃铋镁四联疗法；对照组给予胶体酒石酸铋四联疗法，疗程为14 d。比较两组的Hp根除效果及不良反应发生率。结果治疗组的Hp根除率（85.42%）高于对照组（83.33%），差异无统计学意义（P>0.05）。治疗组和对照组的不良反应发生率分别为6.25%、20.83%，差异有统计学意义（P<0.05）。结论含胃铋镁四联疗法对Hp根除效果显著，且安全性高，值得临床推广。
目的：觀察含胃鉍鎂四聯療法根除幽門螺桿菌（Hp）的臨床療效。方法選擇2014年10月~2015年3月孝感市中心醫院經13C-尿素呼氣試驗確診的96例Hp感染患者為研究對象，隨機分為治療組和對照組，各48例。治療組給予含胃鉍鎂四聯療法；對照組給予膠體酒石痠鉍四聯療法，療程為14 d。比較兩組的Hp根除效果及不良反應髮生率。結果治療組的Hp根除率（85.42%）高于對照組（83.33%），差異無統計學意義（P>0.05）。治療組和對照組的不良反應髮生率分彆為6.25%、20.83%，差異有統計學意義（P<0.05）。結論含胃鉍鎂四聯療法對Hp根除效果顯著，且安全性高，值得臨床推廣。
목적：관찰함위필미사련요법근제유문라간균（Hp）적림상료효。방법선택2014년10월~2015년3월효감시중심의원경13C-뇨소호기시험학진적96례Hp감염환자위연구대상，수궤분위치료조화대조조，각48례。치료조급여함위필미사련요법；대조조급여효체주석산필사련요법，료정위14 d。비교량조적Hp근제효과급불량반응발생솔。결과치료조적Hp근제솔（85.42%）고우대조조（83.33%），차이무통계학의의（P>0.05）。치료조화대조조적불량반응발생솔분별위6.25%、20.83%，차이유통계학의의（P<0.05）。결론함위필미사련요법대Hp근제효과현저，차안전성고，치득림상추엄。
Objective To observe clinical curative effect of quadruple therapy containing bismuth magnesium for eradi-cation of Helicobacter pylori (Hp). Methods 96 Hp-infected patients confirmed by 13C-urea breath test in Xiaogan Central Hospital from October 2014 to March 2015 were selected as study objects,and the were randomly divided into treatment group and control group,and there were 48 cases in each group.Treatment group was given quadruple therapy containing bismuth magnesium,and control group was given colloidal bismuth tartrate-containing quadruple therapy.Hp eradication effect and the incidence rate of adverse reaction was compared respectively between two groups. Results Hp eradication rate of treatment group (85.42%) was higher than that of control group (83.33%),and there was no sta-tistical difference (P>0.05). The incidence rate of adverse reaction in treatment group and control group was 6.25% and 20.83%respectively,and there was a statistical difference (P<0.05). Conclusion Quadruple therapy containing bismuth magnesium has significant effect of Hp eradication and higher security.It is worthy of clinical promotion.
