CAJ | 학술논문

目的：探讨布地奈德雾化吸入联合阿奇霉素治疗儿童支原体肺炎的临床效果。方法选取2013年2月~2015年2月我院收治120例支原体肺炎患儿，将其随机分为观察组和对照组，对照组采用阿奇霉素治疗，观察组在对照组治疗基础上加用布地奈德雾化吸入治疗，比较两组患儿治疗效果及对血清IgE、IL-3、IL-4水平的影响。结果观察组治疗总有效率为98.33%，明显高于对照组的83.33%，两组比较差异有统计学意义（P<0.05）；治疗后观察组患儿血清IgE、IL-3、IL-4水平均低于对照组，两组间各值比较差异有统计学意义（P<0.05）。结论布地奈德雾化吸入佐治儿童支原体肺炎可降低血清IgE、IL-3、IL-4水平，提高治疗效果，值得临床推广应用。
목적：탐토포지내덕무화흡입연합아기매소치료인동지원체폐염적림상효과。방법선취2013년2월~2015년2월아원수치120례지원체폐염환인，장기수궤분위관찰조화대조조，대조조채용아기매소치료，관찰조재대조조치료기출상가용포지내덕무화흡입치료，비교량조환인치료효과급대혈청IgE、IL-3、IL-4수평적영향。결과관찰조치료총유효솔위98.33%，명현고우대조조적83.33%，량조비교차이유통계학의의（P<0.05）；치료후관찰조환인혈청IgE、IL-3、IL-4수평균저우대조조，량조간각치비교차이유통계학의의（P<0.05）。결론포지내덕무화흡입좌치인동지원체폐염가강저혈청IgE、IL-3、IL-4수평，제고치료효과，치득림상추엄응용。
Objective To explore the influence of budesonide aerosol inhalation treating Mycoplasma pneumonia in children on serum IgE,IL-3 and IL-4 level. Methods 120 children with Mycoplasma pneumonia treated in our hospital from February 2013 to February 2015 were selected and divided into two groups randomly,the observation group and the control group.The control group was treated with azithromycin,based on which the control group was treated with budesonide aerosol inhalation.The treatment effect between two groups and the influence on serum IgE,IL-3 and IL-4 level was compared respectively. Results The total effective rate of observation group was 98.33%,and that of control group was 83.33%,with statistical difference (P<0.05).After treatment,the serum IgE,IL-3 and IL-4 level of the obser-vation group was lower than that of control group respectively,with statistical difference (P<0.05). Conclusion Budes-onide aerosol inhalation treating Mycoplasma pneumonia in children can reduce serum IgE,IL-3 and IL-4 level,and im-prove the treatment effect,which is worthy of clinical promotion and application.