中外医学研究
中外醫學研究
중외의학연구
Chinese and Foreign Medical Research
2015年
29期
17-18,19
,共3页
甲状腺癌%微小RNA-363%荧光实时定量聚合酶链反应
甲狀腺癌%微小RNA-363%熒光實時定量聚閤酶鏈反應
갑상선암%미소RNA-363%형광실시정량취합매련반응
Thyroid carcinoma%miRNA-363%Real-time PCR
目的：探讨微小RNA(miRNA)-363在正常人和甲状腺癌患者血清、甲状腺癌组织及正常癌旁组织中的表达。方法：采用实时荧光定量PCR方法检测miRNA-363在正常人和甲状腺癌患者血清中的含量，并检测甲状腺癌组织和正常癌旁组织miRNA-363含量。结果：miRNA-363在甲状腺癌患者血清及甲状腺癌组织中表达均下降，差异均有统计学意义(P<0.05)。结论：miRAN-363在甲状腺癌中表达下降。
目的：探討微小RNA(miRNA)-363在正常人和甲狀腺癌患者血清、甲狀腺癌組織及正常癌徬組織中的錶達。方法：採用實時熒光定量PCR方法檢測miRNA-363在正常人和甲狀腺癌患者血清中的含量，併檢測甲狀腺癌組織和正常癌徬組織miRNA-363含量。結果：miRNA-363在甲狀腺癌患者血清及甲狀腺癌組織中錶達均下降，差異均有統計學意義(P<0.05)。結論：miRAN-363在甲狀腺癌中錶達下降。
목적：탐토미소RNA(miRNA)-363재정상인화갑상선암환자혈청、갑상선암조직급정상암방조직중적표체。방법：채용실시형광정량PCR방법검측miRNA-363재정상인화갑상선암환자혈청중적함량，병검측갑상선암조직화정상암방조직miRNA-363함량。결과：miRNA-363재갑상선암환자혈청급갑상선암조직중표체균하강，차이균유통계학의의(P<0.05)。결론：miRAN-363재갑상선암중표체하강。
Objective:To investigate the expression of miRNA-363 in sera of the normal subjects and patients with thyroid carcinoma,and the expression of miRNA-363 in normal thyroid tissues and thyroid carcinoma tissues in patients.Method:The content of miRNA-363 were tested by real-time PCR,and the content of miRNA-363 were tested on normal thyroid tissues and thyroid carcinoma tissues in patients.Result:Compared to the normal subjects,the level of miRNA-363 were significantly decreased in sera of patients with thyroid carcinoma,there were statistically significant differences(P<0.05).Conclusion:The expression of miRNA-363 in patients with thyroid carcinoma decreases.
