CAJ | 학술논문

目的：探讨醒脑静注射液联合尼莫地平治疗颅脑损伤后脑血管痉挛(CVS)的临床效果。方法：选择2013年3月-2015年3月50例颅脑损伤后出现CVS患者，按照随机数字表法分为观察组和对照组，每组25例。对照组采用尼莫地平治疗，观察组给予醒脑静注射液联合尼莫地平治疗，观察两组患者格拉斯哥昏迷评分(GCS)、大脑中动脉(MCA)收缩峰流速(Vp)和近期疗效。结果：治疗5、10 d后，观察组GCS评分均高于对照组(P<0.05)。治疗2周后，观察组MCA Vp显著低于对照组(P<0.05)。观察组治疗总有效率为96.00%，明显高于对照组的76.00%(P<0.05)。结论：醒脑静注射液联合尼莫地平治疗颅脑损伤后脑血管痉挛疗效佳。
목적：탐토성뇌정주사액연합니막지평치료로뇌손상후뇌혈관경련(CVS)적림상효과。방법：선택2013년3월-2015년3월50례로뇌손상후출현CVS환자，안조수궤수자표법분위관찰조화대조조，매조25례。대조조채용니막지평치료，관찰조급여성뇌정주사액연합니막지평치료，관찰량조환자격랍사가혼미평분(GCS)、대뇌중동맥(MCA)수축봉류속(Vp)화근기료효。결과：치료5、10 d후，관찰조GCS평분균고우대조조(P<0.05)。치료2주후，관찰조MCA Vp현저저우대조조(P<0.05)。관찰조치료총유효솔위96.00%，명현고우대조조적76.00%(P<0.05)。결론：성뇌정주사액연합니막지평치료로뇌손상후뇌혈관경련료효가。
Objective:To investigate the effect of Xingnaojing injection combined with nimodipine on patients with cerebral vasospasm after brain injury.Method:50 cases of patients with cerebral vasospasm after brain injury were selected from March 2013 to March 2015,which were randomly divided into the observation group and the control group,25 cases in each group.The patients in control group were given nimodipine,the observation group were received Xingnaojing injection combined with nimodipine.Glasgow coma score(GCS),the middle cerebral artery(MCA)peak systolic velocity(Vp)and short-term effec were observed in two goups.Result:The GCS in the observation group were significantly higher than that in the control group after 5,10 d’s treatment(P<0.05).After treatment of two weeks,MCA Vp in the observation group was significantly lower than that in the control group(P<0.05).The total effective rate was 96.00% in the observation group,which was significantly higher than that in the control group(76.00%)(P<0.05). Conclusion:Xingnaojing injection significantly improved the efficacy of nimodipine on patients with cerebral vasospasm after brain injury.