国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
International Journal of Laboratory Medicine
2015年
19期
2854-2856
,共3页
红细胞分布宽度%血清尿酸%经皮冠状动脉介入干预%预后
紅細胞分佈寬度%血清尿痠%經皮冠狀動脈介入榦預%預後
홍세포분포관도%혈청뇨산%경피관상동맥개입간예%예후
red cell distribution width%serum uric acid%percutaneous coronary intervention%prognosis
目的：探讨红细胞分布宽度(RDW)与血清尿酸(SUA)水平在接受成功经皮冠状动脉介入(PCI)术的急性冠状动脉综合征(ACS)患者预后评价中的价值。方法152例胸痛症状发作12 h 内接受成功 PCI 治疗的 ACS 患者为研究对象。PCI 术前12 h 内完成 RDW 与 SUA 检测。根据受试者工作特征(ROC)曲线确定的诊断界值分为3组：I 组(RDW<14.5%,SUA<402μmol/L)73例,Ⅱ组(RDW<14.5%,SUA≥402μmol/L；RDW≥14.5%,SUA<402μmol/L)50例,Ⅲ组(RDW≥14.5%,SUA≥402μmol/L)29例。观察分析3组患者术后30 d 全因死亡和心脏联合事件终点(再次血管重建、非致死性心肌梗死、继发心力衰竭、再住院及死亡)的发生率。结果 RDW 和 SUA 术前水平均是术后30 d 全因死亡的独立相关因素,两者呈线性相关(r=0.336,P =0.001)。3组间比较患者30 d 心脏联合事件发生率和全因死亡差异有统计学意义(P =0.031,P =0.012)。结论接受成功 PCI 术前 RDW≥14.5%且 SUA≥402μmol/L 的 ACS 患者预后不良,RDW 和 SUA 联合检测,对尽早筛选出高危患者,及时优化干预策略具有重要价值。
目的：探討紅細胞分佈寬度(RDW)與血清尿痠(SUA)水平在接受成功經皮冠狀動脈介入(PCI)術的急性冠狀動脈綜閤徵(ACS)患者預後評價中的價值。方法152例胸痛癥狀髮作12 h 內接受成功 PCI 治療的 ACS 患者為研究對象。PCI 術前12 h 內完成 RDW 與 SUA 檢測。根據受試者工作特徵(ROC)麯線確定的診斷界值分為3組：I 組(RDW<14.5%,SUA<402μmol/L)73例,Ⅱ組(RDW<14.5%,SUA≥402μmol/L；RDW≥14.5%,SUA<402μmol/L)50例,Ⅲ組(RDW≥14.5%,SUA≥402μmol/L)29例。觀察分析3組患者術後30 d 全因死亡和心髒聯閤事件終點(再次血管重建、非緻死性心肌梗死、繼髮心力衰竭、再住院及死亡)的髮生率。結果 RDW 和 SUA 術前水平均是術後30 d 全因死亡的獨立相關因素,兩者呈線性相關(r=0.336,P =0.001)。3組間比較患者30 d 心髒聯閤事件髮生率和全因死亡差異有統計學意義(P =0.031,P =0.012)。結論接受成功 PCI 術前 RDW≥14.5%且 SUA≥402μmol/L 的 ACS 患者預後不良,RDW 和 SUA 聯閤檢測,對儘早篩選齣高危患者,及時優化榦預策略具有重要價值。
목적：탐토홍세포분포관도(RDW)여혈청뇨산(SUA)수평재접수성공경피관상동맥개입(PCI)술적급성관상동맥종합정(ACS)환자예후평개중적개치。방법152례흉통증상발작12 h 내접수성공 PCI 치료적 ACS 환자위연구대상。PCI 술전12 h 내완성 RDW 여 SUA 검측。근거수시자공작특정(ROC)곡선학정적진단계치분위3조：I 조(RDW<14.5%,SUA<402μmol/L)73례,Ⅱ조(RDW<14.5%,SUA≥402μmol/L；RDW≥14.5%,SUA<402μmol/L)50례,Ⅲ조(RDW≥14.5%,SUA≥402μmol/L)29례。관찰분석3조환자술후30 d 전인사망화심장연합사건종점(재차혈관중건、비치사성심기경사、계발심력쇠갈、재주원급사망)적발생솔。결과 RDW 화 SUA 술전수평균시술후30 d 전인사망적독립상관인소,량자정선성상관(r=0.336,P =0.001)。3조간비교환자30 d 심장연합사건발생솔화전인사망차이유통계학의의(P =0.031,P =0.012)。결론접수성공 PCI 술전 RDW≥14.5%차 SUA≥402μmol/L 적 ACS 환자예후불량,RDW 화 SUA 연합검측,대진조사선출고위환자,급시우화간예책략구유중요개치。
Objective To evaluate the prognostic value of combing pre-procedural red cell distribution width(RDW)with serum uric acid(SUA)levels in patients with acute coronary syndrome(ACS)undergoing percutaneous coronary intervention(PCI).Meth-ods A total of 1 52 consecutive patients with ACS who underwent successful PCI within 12 hours after onset of symptom were en-rolled.RDW and SUA were determined within 12 hours before PCI.The patients were divided into 3 groups according to the cut-off values showed by receiver operating characteristic(ROC)curve:73 cases in group I,RDW<14.5% and SUA<402 μmol/L;50 cases in group Ⅱ,RDW< 14.5% and SUA≥ 402 μmol/L,RDW≥ 14.5% and SUA< 402 μmol/L;29 patients in group Ⅲ,RDW>14.5% and SUA>402 μmol/L.The pre-procedural RDW and SUA status associated with 30 days any cause mortality and major adverse combined cardiac events including revascularization,non-fatal recurrent myocardial infarction,secondary heart failure,rehos-pitalization and death were analyzed.Results Pre-procedural RDW and SUA level predicted 30 days cardiac mortality,RDW and SUA level correlated linearly(r=0.336,P =0.001).30 days major adverse combined cardiac events and any cause mortality were significantly different among the three groups(P =0.031,P =0.012).Conclusion Pre-procedural RDW≥ 14.5% and SUA≥402μmol/L indicates poor prognosis in ACS patients underwent successful PCI.Therefore the combination of RDW and SUA measure-ment should be taken into consideration for risk stratification to decide about the management strategies in ACS patients.
