CAJ | 학술논문

目的：探讨检测丙型肝炎病毒(HCV)抗体(HCV-Ab)、HCV核心抗原(HCV-cAg)、HCV核糖核酸(HCV-RNA)对丙型肝炎诊断的价值。方法258例该院 HCV 患者为研究对象,采用荧光定量 PCR 检测 HCV-RNA,同时采用双抗原夹心酶联免疫法定性检测 HCV-Ab,双抗体夹心酶联免疫法定性检测 HCV-cAg,并进行比较。结果 HCV-Ab 分别与 HCV-cAg、HCV-RNA 检测结果差异有统计学意义(P <0.05),HCV-cAg 与 HCV-RNA 检测结果差异无统计学意义(P >0.05)。结论 HCV-cAg 与 HCV-RNA 检测符合率高,与 HCV-Ab 互为补充,可对 HCV 感染做到早期检测,防止漏检,提高检出率。
목적：탐토검측병형간염병독(HCV)항체(HCV-Ab)、HCV핵심항원(HCV-cAg)、HCV핵당핵산(HCV-RNA)대병형간염진단적개치。방법258례해원 HCV 환자위연구대상,채용형광정량 PCR 검측 HCV-RNA,동시채용쌍항원협심매련면역법정성검측 HCV-Ab,쌍항체협심매련면역법정성검측 HCV-cAg,병진행비교。결과 HCV-Ab 분별여 HCV-cAg、HCV-RNA 검측결과차이유통계학의의(P <0.05),HCV-cAg 여 HCV-RNA 검측결과차이무통계학의의(P >0.05)。결론 HCV-cAg 여 HCV-RNA 검측부합솔고,여 HCV-Ab 호위보충,가대 HCV 감염주도조기검측,방지루검,제고검출솔。
Objective To compare the clinical value of hepatitis C virus (HCV)antibody(HCV-Ab),hepatitis C virus core anti-gen (HCV-cAg),hepatitis C virus ribonucleic acid (HCV-RNA)in diagnosis for hepatitis C.Methods A total of 258 patients with hepatitis C were recruited in this study,HCV-RNA was detected by fluorescence quantitative PCR detection,HCV-Ab and HCV-cAg were detected by the double antigen sandwich ELISA statutory,and the test data was analyze.Results The result of HCV-Ab detection was significant difference with those of HCV-cAg and HCV-RNA detection respectively(P <0.05),HCV-cAg and HCV-RNA detection had no significant difference (P >0.05).Conclusion The coincidence rate of HCV-cAg detection and HCV-RNA detection was high,and complement with HCV-Ab,the early detection could be done to prevent the omission of HCV infection and to improve the detection rate.