CAJ | 학술논문

目的：对中国人民解放军第44医院2011年1月至2013年12月住院患者感染铜绿假单胞菌的分布情况及耐药性进行调查。方法对2011年1月至2013年12月住院患者送检临床标本中分离铜绿假单胞菌的分布情况及耐药性进行回顾性分析。结果3年时间共分离出铜绿假单胞菌642株,其中57.0%来源于痰液标本,27.9%来源于伤口分泌物。感染病区以骨外科、ICU、老年病科及呼吸内科最为常见,分别占22.9%、20.1%、18.8%和15.9%。药敏结果显示铜绿假单胞菌对多黏菌素最为敏感,对复方磺胺甲噁唑、氨苄西林、头孢唑林100.0%耐药,对氨苄西林/舒巴坦、头孢曲松的耐药率高于90.0%。结论铜绿假单胞菌主要引起住院患者下呼吸道及术后伤口感染,其对常用抗菌药物耐药严重,临床应根据药敏结果合理应用抗菌药物。
목적：대중국인민해방군제44의원2011년1월지2013년12월주원환자감염동록가단포균적분포정황급내약성진행조사。방법대2011년1월지2013년12월주원환자송검림상표본중분리동록가단포균적분포정황급내약성진행회고성분석。결과3년시간공분리출동록가단포균642주,기중57.0%래원우담액표본,27.9%래원우상구분비물。감염병구이골외과、ICU、노년병과급호흡내과최위상견,분별점22.9%、20.1%、18.8%화15.9%。약민결과현시동록가단포균대다점균소최위민감,대복방광알갑오서、안변서림、두포서림100.0%내약,대안변서림/서파탄、두포곡송적내약솔고우90.0%。결론동록가단포균주요인기주원환자하호흡도급술후상구감염,기대상용항균약물내약엄중,림상응근거약민결과합리응용항균약물。
Objective To analyze the popular characteristic and drug resistance of Pseudomonas aeruginosa in a hospital of Guiy-ang from January 201 1 to December 2013.Methods The distribution characteristic and drug resistance of Pseudomonas aeruginosa isolated from clinical samples from January 201 1 to December 2013 were analyzed retrospectively.Results A total of 642 strains of Pseudomonas aeruginosa were isolated for three years in our hospital from January 201 1 to December 2013,there was 57.0% isola-ted from sputum specimens,and 27.9% isolated from excreta of wound.The infected endemic area distribution was made up of Or-thopedic Surgery,ICU,Geriatrics Department and Respiratory Department accounting for 22.9%,20.1%,18.8% and 1 5.9% re-spectively.Pseudomonas aeruginosa was most sensitive to polymyxin bacillosporin.The drug resistance rates to Trimethoprim,Am-picillin and Cefazolin were all 100.0%.The drug resistance rates to Ampicillin/sulbactam and Ceftriaxone were 90.0%. Conclusion Pseudomonas aeruginosa is the main cause of lower respiratory tract infections in patients and wound infection and show serious multi-drug resistant,so it is necessary to use drugs reasonably according to the drug susceptibility results.