CAJ | 학술논문

目的：了解武警新疆总队医院妇科门诊患者生殖道支原体的感染情况及药敏试验结果,为临床合理用药提供实验室依据。方法采用支原体分离培养药敏试剂盒对1067份妇科门诊患者的生殖道分泌物标本进行支原体鉴定及药物敏感分析。结果1067份标本中,检测出支原体阳性标本659份,其中解脲脲原体(Uu)阳性占72.99%(481/659),人型支原体(Mh)阳性占3.79%(25/659),Uu 与 Mh 混合阳性占23.22%(153/659),对12种抗菌药物的药敏结果显示,单一感染 Uu 较敏感的药物有交沙霉素、强力霉素、美满霉素、四环素、克拉霉素、阿奇霉素、罗红霉素；单一感染 Mh 较敏感的药物有强力霉素、交沙霉素、美满霉素、四环素；Uu 与 Mh 混合感染较敏感的药物有交沙霉素、美满霉素、强力霉素。结论该院支原体感染主要以 Uu 感染为主,不论是单一 Uu 感染还是 Uu 与 Mh 混合感染,在抗菌药物的敏感性上都有差异,临床医生应根据患者情况依照药敏结果合理选择抗菌药物,降低耐药率。
목적：료해무경신강총대의원부과문진환자생식도지원체적감염정황급약민시험결과,위림상합리용약제공실험실의거。방법채용지원체분리배양약민시제합대1067빈부과문진환자적생식도분비물표본진행지원체감정급약물민감분석。결과1067빈표본중,검측출지원체양성표본659빈,기중해뇨뇨원체(Uu)양성점72.99%(481/659),인형지원체(Mh)양성점3.79%(25/659),Uu 여 Mh 혼합양성점23.22%(153/659),대12충항균약물적약민결과현시,단일감염 Uu 교민감적약물유교사매소、강력매소、미만매소、사배소、극랍매소、아기매소、라홍매소；단일감염 Mh 교민감적약물유강력매소、교사매소、미만매소、사배소；Uu 여 Mh 혼합감염교민감적약물유교사매소、미만매소、강력매소。결론해원지원체감염주요이 Uu 감염위주,불론시단일 Uu 감염환시 Uu 여 Mh 혼합감염,재항균약물적민감성상도유차이,림상의생응근거환자정황의조약민결과합리선택항균약물,강저내약솔。
Objective To investigate the incidence and the drug-sensitivity results of mycoplasma infection in genital tract from the gynecological outpatients,in order to provide a laboratory evidence for clinical rational use of drug.Methods The drug sensitiv-ity kit was used for isolation and culture of mycoplasma,reproductive tract secretions samples of 1 067 cases of gynecological pa-tients were collected to do mycoplasma identification and drug sensitivity test.Results In 1 067 samples,the positive rate of myco-plasma were 659 samples,including ureaplasma urealyticum(Uu)positive rate was 72.99%(481/659),mycoplasma hominis (Mh) positive rate was 3.79%(25/659),Uu and Mh positive rate accounted for 23.22%(1 53/659).The drug sensitivity results of 12 kinds of antimicrobial agents showed that single infection Uu was more sensitive to josamycin,doxycycline,minocycline,tetracy-cline,clarithromycin,azithromycin and roxithromycin.Single infection Mh was more sensitive to doxycycline,josamycin,minocycline and tetracycline.Mixed infection of Uu and Mh was more sensitive to josamycin,minocycline and doxycycline.Conclusion The main pathogen isolated from patients infected with plasma in our hospital is Uu,whether single Uu or Uu,Mh mixed infection,there are differences in the sensitivity of antimicrobial,clinicians should use drug rationally according to the conditions of patients and drug sensitivity results to reduce drug resistance rate.