中西医结合研究
中西醫結閤研究
중서의결합연구
Research of Integrated Traditional Chinese and Western Medicine
2015年
4期
173-175
,共3页
意识障碍%中药灌肠%大黄承气汤%炎性物质
意識障礙%中藥灌腸%大黃承氣湯%炎性物質
의식장애%중약관장%대황승기탕%염성물질
disturbance of unconsciousness%traditional Chinese medicine enema%modified Dahuangchengqi de-coction%inflammatory substances
目的：评价改良大黄承气汤灌肠治疗重型意识障碍患者的效果。方法将重型意识障碍患者300例随机分为对照组及观察组，每组各150例，对照组给予生理盐水灌肠，观察组采用改良大黄承气汤灌肠，比较2组治疗前后白细胞（WBC）、中性粒细胞（NEU ）、淋巴细胞（LYM ）及 C‐反应蛋白（CRP）水平，以及意识障碍持续时间、格拉斯哥昏迷评分（GCS ）及住院时间的差异。结果治疗后，2组WBC、NEU 、LYM 及CRP均有不同程度下降，与治疗前比较差异有统计学意义（P＜0.05），且观察组WBC、NEU 、LYM 及CRP均显著低于对照组（P＜0.05）；观察组患者的意识障碍持续时间及住院时间显著缩短GCS评分显著升高，与对照组比较差异有统计学意义（P＜0.05，P＜0.01）。结论改良大黄承气汤灌肠治疗重型意识障碍有效。
目的：評價改良大黃承氣湯灌腸治療重型意識障礙患者的效果。方法將重型意識障礙患者300例隨機分為對照組及觀察組，每組各150例，對照組給予生理鹽水灌腸，觀察組採用改良大黃承氣湯灌腸，比較2組治療前後白細胞（WBC）、中性粒細胞（NEU ）、淋巴細胞（LYM ）及 C‐反應蛋白（CRP）水平，以及意識障礙持續時間、格拉斯哥昏迷評分（GCS ）及住院時間的差異。結果治療後，2組WBC、NEU 、LYM 及CRP均有不同程度下降，與治療前比較差異有統計學意義（P＜0.05），且觀察組WBC、NEU 、LYM 及CRP均顯著低于對照組（P＜0.05）；觀察組患者的意識障礙持續時間及住院時間顯著縮短GCS評分顯著升高，與對照組比較差異有統計學意義（P＜0.05，P＜0.01）。結論改良大黃承氣湯灌腸治療重型意識障礙有效。
목적：평개개량대황승기탕관장치료중형의식장애환자적효과。방법장중형의식장애환자300례수궤분위대조조급관찰조，매조각150례，대조조급여생리염수관장，관찰조채용개량대황승기탕관장，비교2조치료전후백세포（WBC）、중성립세포（NEU ）、림파세포（LYM ）급 C‐반응단백（CRP）수평，이급의식장애지속시간、격랍사가혼미평분（GCS ）급주원시간적차이。결과치료후，2조WBC、NEU 、LYM 급CRP균유불동정도하강，여치료전비교차이유통계학의의（P＜0.05），차관찰조WBC、NEU 、LYM 급CRP균현저저우대조조（P＜0.05）；관찰조환자적의식장애지속시간급주원시간현저축단GCS평분현저승고，여대조조비교차이유통계학의의（P＜0.05，P＜0.01）。결론개량대황승기탕관장치료중형의식장애유효。
Objective To evaluate the effect of modified Dahuangchengqi decoction enema for the treatment of patients with severe coma.Methods 300 patients with severe coma were randomly divided into the control group and the observation group(n=150).Patients in the control group received the saline enema while patients in the observation group received the enema with modified Dahuangchengqi decoction.White blood cell(WBC) ,neutro‐phils(NEU),lymphocyte(LYM)and C‐reactive protein(CRP)levels were examined before and after the treat‐ment.The duration of unconsciousness ,Glasgow Coma Scale(GCS) and the length of hospitalization were also compared.Results Compared with the pre‐treatment ,blood WBC ,NEU ,LYM and CRP levels were decreased in both groups.Compared with the control group ,the above inflammatory markers were significantly reduced in the observation group(P<0.05).Moreover ,compared with the control group ,the duration of unconsciousness and the length of hospitalization were reduced while GCS score were elevated in the observation group(P< 0.05 ,P<0.01) .Conclusion M odified Dahuangchengqi decoction is effective in the treatment of severe coma.
