世界最新医学信息文摘（连续型电子期刊）
世界最新醫學信息文摘（連續型電子期刊）
세계최신의학신식문적（련속형전자기간）
World Latest Medicine Information
2015年
65期
1-2
,共2页
无创机械通气%COPD%呼吸衰竭
無創機械通氣%COPD%呼吸衰竭
무창궤계통기%COPD%호흡쇠갈
Noninvasive mechanical ventilation%COPD%Respiratory failure
目的：观察无创正压通气在治疗急性加重期的慢性阻塞性肺疾病合并有II型呼吸衰竭的治疗效果，探讨无创正压通气在治疗COPD合并Ⅱ型呼吸衰竭中的应用价值。为更好的应用无创正压通气的提供临床适应证指导。方法选择我院收治的60例COPD合并Ⅱ型呼吸衰竭病患作为研究对象，随机分为对照组和治疗组，每组各30例，两组病患均给予吸氧、祛痰、抗感染、针对基础疾病及并发症的治疗，治疗组在给予常规治疗的同时加用无创正压通气的治疗，运用急性生理学及慢性健康状况系统评分Ⅱ（ APACHEⅡ评分）为标准，观察两组患者在治疗前后的心率、呼吸频率、血气分析和临床指标变化。结果两组患者经过治疗后pHPaO2、PaCO2等血气指标好于治疗之前，差异有统计学意义（P＜0.05），治疗组较对照组改善更加明显（P＜0.05）；与对照组相比较，治疗组患者的住院日、气管插管次数均有下降或缩短，差异有统计学意义（P＜0.05）。结论慢性阻塞性肺疾病合并有II型呼吸衰竭在常规治疗同时运用无创正压通气可以提高治疗疗效，降低并发症发生率，值得临床借鉴。
目的：觀察無創正壓通氣在治療急性加重期的慢性阻塞性肺疾病閤併有II型呼吸衰竭的治療效果，探討無創正壓通氣在治療COPD閤併Ⅱ型呼吸衰竭中的應用價值。為更好的應用無創正壓通氣的提供臨床適應證指導。方法選擇我院收治的60例COPD閤併Ⅱ型呼吸衰竭病患作為研究對象，隨機分為對照組和治療組，每組各30例，兩組病患均給予吸氧、祛痰、抗感染、針對基礎疾病及併髮癥的治療，治療組在給予常規治療的同時加用無創正壓通氣的治療，運用急性生理學及慢性健康狀況繫統評分Ⅱ（ APACHEⅡ評分）為標準，觀察兩組患者在治療前後的心率、呼吸頻率、血氣分析和臨床指標變化。結果兩組患者經過治療後pHPaO2、PaCO2等血氣指標好于治療之前，差異有統計學意義（P＜0.05），治療組較對照組改善更加明顯（P＜0.05）；與對照組相比較，治療組患者的住院日、氣管插管次數均有下降或縮短，差異有統計學意義（P＜0.05）。結論慢性阻塞性肺疾病閤併有II型呼吸衰竭在常規治療同時運用無創正壓通氣可以提高治療療效，降低併髮癥髮生率，值得臨床藉鑒。
목적：관찰무창정압통기재치료급성가중기적만성조새성폐질병합병유II형호흡쇠갈적치료효과，탐토무창정압통기재치료COPD합병Ⅱ형호흡쇠갈중적응용개치。위경호적응용무창정압통기적제공림상괄응증지도。방법선택아원수치적60례COPD합병Ⅱ형호흡쇠갈병환작위연구대상，수궤분위대조조화치료조，매조각30례，량조병환균급여흡양、거담、항감염、침대기출질병급병발증적치료，치료조재급여상규치료적동시가용무창정압통기적치료，운용급성생이학급만성건강상황계통평분Ⅱ（ APACHEⅡ평분）위표준，관찰량조환자재치료전후적심솔、호흡빈솔、혈기분석화림상지표변화。결과량조환자경과치료후pHPaO2、PaCO2등혈기지표호우치료지전，차이유통계학의의（P＜0.05），치료조교대조조개선경가명현（P＜0.05）；여대조조상비교，치료조환자적주원일、기관삽관차수균유하강혹축단，차이유통계학의의（P＜0.05）。결론만성조새성폐질병합병유II형호흡쇠갈재상규치료동시운용무창정압통기가이제고치료료효，강저병발증발생솔，치득림상차감。
Objective Observation of noninvasive positive pressure ventilation with type II respiratory failure treatment effect in the combined treatment of acute exacerbations of chronic obstructive pulmonary disease.To explore the application value of noninvasive positive pressure ventilation in the treatment of COPD with type II respiratory failure.For the better application of noninvasive positive pressure ventilation to provide clinical indications guidance.Methods In our hospital treated 60 cases of COPD with type II respiratory failure patients as the research object.30 cases in each group were randomly divided into control group and treatment group.Two groups of patients were given the treatment of oxygen, expectorant, anti infection, according to the basis of disease and complications.In the treatment grouptherapy and routine therapy combined with noninvasive positive pressure ventilation.The use of Acute Physiology and Chronic Health Evaluation II(APACHE score II) as the standard.The two groups were observed before and after treatment in the heart rate,respiratory rate,blood gas analysis and clinical index changes.ResultsThe patients in the two groups after treatment pHPaO2, PaCO2 of blood gas indexes better than before treatment, the difference was statistically signiifcant (P < 0.05).The treatment group than the control group improved more obviously (P < 0.05).Compared with the control group, the treatment group patients hospitalization days, tracheal intubation declined or shorten.The difference was statistically significant (P < 0.05).ConclusionCombined with chronic obstructive pulmonary disease with type II respiratory failure at the same time the use of noninvasive positive pressure ventilation can improve the therapeutic effect in the conventional treatment.Noninvasive positive pressure ventilation reduce the incidence of complications.It is worthy of clinical reference.
