CAJ | 학술논문

目的：探讨体表降温及血管内降温治疗急性重型颅脑外伤的安全性。方法选择急性重型颅脑外伤患者30例，采用随机数字表法分为体表降温组（A组，n＝15）和血管内降温组（B组，n＝15），对比两组患者达到目标降温温度时间、偏离目标温度1℃发生率、患者出现低血压、心率失常及电解质紊乱等并发症的发生率及达到目标复温温度时间。结果两组达到目标降温温度时间、达到目标复温温度时间及偏离目标温度1℃发生率比较差异有统计学意义（ P＜0.05）。出现低血压、心率失常及电解质紊乱等并发症发生率比较差异无统计学意义（ P＞0.05）。结论血管内降温具有降温速度快、维持目标体温平稳、复温简单平稳及并发症发生率低等特点，具有良好的安全性。
목적：탐토체표강온급혈관내강온치료급성중형로뇌외상적안전성。방법선택급성중형로뇌외상환자30례，채용수궤수자표법분위체표강온조（A조，n＝15）화혈관내강온조（B조，n＝15），대비량조환자체도목표강온온도시간、편리목표온도1℃발생솔、환자출현저혈압、심솔실상급전해질문란등병발증적발생솔급체도목표복온온도시간。결과량조체도목표강온온도시간、체도목표복온온도시간급편리목표온도1℃발생솔비교차이유통계학의의（ P＜0.05）。출현저혈압、심솔실상급전해질문란등병발증발생솔비교차이무통계학의의（ P＞0.05）。결론혈관내강온구유강온속도쾌、유지목표체온평은、복온간단평은급병발증발생솔저등특점，구유량호적안전성。
Objective To explore the safety of two kinds of mild hypothermia in the treatment of acute severe brain injury.Methods Thirty patients were randomly divided into group A( treated with surface cooling) and group B ( treated with endovascular hypothermia) .The time to reach target cooling temperature, the incidence of 1℃devia-ted from the target temperature hypotension rate, heart arrhythmia rate and electrolyte disorder rate and other compli-cations were compared between the two groups.Results There were significant differences in the target cooling tem-perature time and the incidence of 1 ℃ deviated from the target temperature between the two groups ( P<0.05 ) . There were no significant differences in hypotension rate, heart arrhythmia rate, electrolyte disorder rate and other complications between the two groups(P>0.05).Conclusion Endovascular cooling is a safe and efficient treatment method for quickly maintaining the target temperature with features of simplicity, stability and less complications.