CAJ | 학술논문

目的：探讨电导率在肾脏疾病中的变化及其与血清胱抑素C(CysC)水平的相关性。方法该院住院患者723例,其中 IgA 肾病组81例,糖尿病肾病组104例,肾病综合征组130例,多发性骨髓瘤组89例,慢性肾小球肾炎组115例,肾结石组101例,慢性肾脏衰竭组103例。同期体检健康者205例纳入对照组。采用 Sysmex 公司生产的 UF-1000i 全自动尿沉渣分析仪测定尿电导率,日立7600全自动生化分析仪测定 CysC,采用 SPSS19.0软件比较各组指标,并对2项指标进行相关分析。结果各疾病组尿电导率均低于对照组,差异有统计学意义(P <0.05)。各疾病组尿电导率与 CysC 水平呈负相关(P <0.05)。结论电导率测定对反映肾脏疾病患者肾脏浓缩功能的变化及肾小球功能状况有一定的临床价值。
목적：탐토전도솔재신장질병중적변화급기여혈청광억소C(CysC)수평적상관성。방법해원주원환자723례,기중 IgA 신병조81례,당뇨병신병조104례,신병종합정조130례,다발성골수류조89례,만성신소구신염조115례,신결석조101례,만성신장쇠갈조103례。동기체검건강자205례납입대조조。채용 Sysmex 공사생산적 UF-1000i 전자동뇨침사분석의측정뇨전도솔,일립7600전자동생화분석의측정 CysC,채용 SPSS19.0연건비교각조지표,병대2항지표진행상관분석。결과각질병조뇨전도솔균저우대조조,차이유통계학의의(P <0.05)。각질병조뇨전도솔여 CysC 수평정부상관(P <0.05)。결론전도솔측정대반영신장질병환자신장농축공능적변화급신소구공능상황유일정적림상개치。
Objective To investigate the changes of urine conductivity in common kidney diseases and the relationship between urine conductivity and cystatin C.Methods A total of 723 patients in the First Affiliated Hospital of Dalian Medical University were selected in this study and divided into IgA nephropathy group(81 patients),diabetic nephropathy group(104 patients),ne-phritic syndrome group(130 patients),multiple myeloma group(89 patients),chronic glomerulonephritis group(1 1 5 patients),renal calculus group(101 patients)and chronic renal failure group(103 patients).Other 205 healthy persons were recruited into control group.The urine samples were analyzed by Sysmex automatic urinary sediment analyzer UF 1000i to determine the urine conductivi-ty,while the serum samples were analyzed by Hitachi automatic biochemical analyzer 7600 to determine the cystatin C.All the re-sults were statistically analyzed by SPSS1 9.0 software.Results The urine conductivity in kidney patients was significant lower than that of healthy people (P <0.05).There was a significant negative correlation between urine conductivity and the cystatin C in the kidney patients(P <0.05).Conclusion The urine conductivity might serve as an important index in evaluating the kidney func-tion and urine concentration.