CAJ | 학술논문

目的：评价降钙素原(PCT)、C反应蛋白(CRP)、白细胞(WBC)对成年及老年社区获得性肺炎(CAP)严重程度的预测价值。方法2013年5月至2014年9月入院的112例 CAP 住院患者分为成年组(50例)和老年组(62例)。比较2年龄组重症、非重症肺炎患者的 PCT、CRP、WBC 水平,并分析各炎性反应指标与肺炎严重度指数(PSI)、英国胸科协会改良肺炎(CURB-65)评分的相关性。结果成年组及老年组重症肺炎患者的 PCT、CRP 水平及 PSI、CURB-65评分均高于同组非重症肺炎患者(P <0.05)。老年组患者的 PCT 与 PSI、CURB-65评分呈正相关(P <0.05),而成年组患者 PCT,2年龄组患者的 CRP 及 WBC 与PSI、CURB-65评分无显著相关(P >0.05)。结论PCT、CRP 可用于评估成年人及老年人 CAP 的严重程度,而 PCT 在老年 CAP患者中的预测价值较高。
목적：평개강개소원(PCT)、C반응단백(CRP)、백세포(WBC)대성년급노년사구획득성폐염(CAP)엄중정도적예측개치。방법2013년5월지2014년9월입원적112례 CAP 주원환자분위성년조(50례)화노년조(62례)。비교2년령조중증、비중증폐염환자적 PCT、CRP、WBC 수평,병분석각염성반응지표여폐염엄중도지수(PSI)、영국흉과협회개량폐염(CURB-65)평분적상관성。결과성년조급노년조중증폐염환자적 PCT、CRP 수평급 PSI、CURB-65평분균고우동조비중증폐염환자(P <0.05)。노년조환자적 PCT 여 PSI、CURB-65평분정정상관(P <0.05),이성년조환자 PCT,2년령조환자적 CRP 급 WBC 여PSI、CURB-65평분무현저상관(P >0.05)。결론PCT、CRP 가용우평고성년인급노년인 CAP 적엄중정도,이 PCT 재노년 CAP환자중적예측개치교고。
Objective To evaluate the predictive value of procalcitonin (PCT),C-reactive protein (CRP)and white blood cell (WBC)for the severity of community-acquired pneumonia(CAP)in adult and elderly patients.Methods A total of 1 12 hospitalized patients with community acquired pneumonia from May 2013 to September 2014 were selected,and they were divided into the adult group(n=50)and the elderly group (n =62).The PCT,CRP and WBC levels in patients with severe and non-severe pneumonia were compared,and the correlation between those inflammatory markers and pneumonia severity index (PSI),British Thoracic Soci-ety CURB-65 Score(CRUB-65)were analyzed in each age group.Results PCT and CRP levels,PSI and CURB-65 scores in adult and elderly patients with severe pneumonia were higher than those in patients with non-severe pneumonia of corresponding age group (P < 0.05 ).Moreover,PCT had significant positive correlation with PSI and CURB-65 scores in the elderly group (P <0.05).But no correlation were found between the two kinds of scores and PCT in adult group as well as CRP,WBC in the two age group(P >0.05).Conclusion PCT and CRP might be useful markers to evaluate the severity of CAP,and PCT has a higher pre-dictive value in elderly patients with CAP.