中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
26期
61-63,66
,共4页
肝门部胆管癌%治疗方法%效果%生存率
肝門部膽管癌%治療方法%效果%生存率
간문부담관암%치료방법%효과%생존솔
Hilar cholangiocarcinoma%Theray%Effect%Survival rate
目的：探讨肝门部胆管癌的不同治疗方法的效果。方法回顾性分析2012年1月~2013年9月在我院治疗的47例肝门部胆管癌的临床资料。结果47例中根治性手术切除11例,姑息性切除16例,单纯引流20例。根治组平均生存时间为14.5个月,6、12、18个月生存率分别为90.9%、72.7%、54.5%。姑息组中位生存时间为9.1个月,6、12、18个月生存率分别为81.3%、43.8%、25.0%。引流组中位生存时间为5.8个月,6、12、18个月生存率分别为50.0%、25.0%,10.0%。3组的中位生存期差异有统计学意义(P<0.05)。结论根治性切除是治疗肝门部胆管癌最有效的方法,而联合肝叶的切除及区域淋巴结的清扫可以提高其根治性切除率。对于晚期没有根治机会的患者,也应积极地姑息切除,对无法手术切除的患者要积极通畅引流,以缓解症状,提高患者的生活质量,延长其生命。
目的：探討肝門部膽管癌的不同治療方法的效果。方法迴顧性分析2012年1月~2013年9月在我院治療的47例肝門部膽管癌的臨床資料。結果47例中根治性手術切除11例,姑息性切除16例,單純引流20例。根治組平均生存時間為14.5箇月,6、12、18箇月生存率分彆為90.9%、72.7%、54.5%。姑息組中位生存時間為9.1箇月,6、12、18箇月生存率分彆為81.3%、43.8%、25.0%。引流組中位生存時間為5.8箇月,6、12、18箇月生存率分彆為50.0%、25.0%,10.0%。3組的中位生存期差異有統計學意義(P<0.05)。結論根治性切除是治療肝門部膽管癌最有效的方法,而聯閤肝葉的切除及區域淋巴結的清掃可以提高其根治性切除率。對于晚期沒有根治機會的患者,也應積極地姑息切除,對無法手術切除的患者要積極通暢引流,以緩解癥狀,提高患者的生活質量,延長其生命。
목적：탐토간문부담관암적불동치료방법적효과。방법회고성분석2012년1월~2013년9월재아원치료적47례간문부담관암적림상자료。결과47례중근치성수술절제11례,고식성절제16례,단순인류20례。근치조평균생존시간위14.5개월,6、12、18개월생존솔분별위90.9%、72.7%、54.5%。고식조중위생존시간위9.1개월,6、12、18개월생존솔분별위81.3%、43.8%、25.0%。인류조중위생존시간위5.8개월,6、12、18개월생존솔분별위50.0%、25.0%,10.0%。3조적중위생존기차이유통계학의의(P<0.05)。결론근치성절제시치료간문부담관암최유효적방법,이연합간협적절제급구역림파결적청소가이제고기근치성절제솔。대우만기몰유근치궤회적환자,야응적겁지고식절제,대무법수술절제적환자요적겁통창인류,이완해증상,제고환자적생활질량,연장기생명。
Objective To explore the effect of different therapy in the treatment of hilar cholangiocarcinoma (HCC). Methods The data of the 47 patients with HCC treated in our hospital from January 2012 and September 2013 was an-alyzed retrospectively. Results Among 47 patients,11 cases for radical resection,16 cases for palliative resection and 20 received simple drainage.The average survival time for radical resection group was 14.5 months,and 6 months,12 months, 18 months survival rate was 90.0%,72.7%and 54.5% respectively.The media survival time for palliative resec-tion group was 9.1 months,and the 6 months,12 months,18 months survival rate was 81.3%,43.8% and 25.0% respec-tively.The media survival time for simple drainage was 5.8 months,and the 6 months,12 months,18 months survival rate was 50.0%,25.0% and 10.0% respectively.Significant difference was found among three groups (P<0.05). Conclusion Radical resection is the most effective treating HCC,and extend resection of liver lobes and lymph node can improve the radical resection rate.For patients who has no chance for radical resection,palliative resection should be selected, and positive and open drainage should be done for patients who has no chance for resection to ease symptom and im-prove the life-quality of patients and prolong life of patients.
