中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
26期
70-72,75
,共4页
人免疫球蛋白%小儿重症肺炎%临床疗效
人免疫毬蛋白%小兒重癥肺炎%臨床療效
인면역구단백%소인중증폐염%림상료효
Human immunoglobulin%Pediatric severe pneumonia%Clinical efficacy
目的：探讨人免疫球蛋白辅助治疗小儿重症肺炎的临床效果。方法选取本院2013年6月~2014年11月收治的80例小儿重症肺炎患者作为研究对象，随机分成观察组和对照组，各40例。对照组采用常规治疗，包括抗生素治疗、抗病毒治疗、吸氧以及纠正患者心力衰竭等。观察组在对照组的基础上给予人免疫球蛋白辅助治疗，比较两组的治疗效果。结果观察组的治疗总有效率显著高于对照组，差异有统计学意义(P<0.05)。观察组患者的退热时间、咳嗽消失时间、啰音消失时间、X线胸片检查炎症吸收时间以及总住院时间显著短于对照组，差异有统计学意义(P<0.05)。观察组治疗后的IgG水平显著低于对照组，差异有统计学意义(P<0.05)。结论人免疫球蛋白辅助治疗小儿重症肺炎效果显著，能够有效缩短退热时间、咳嗽消失时间、啰音消失时间、X线胸片检查炎症吸收时间以及总住院时间，降低患者血清中的IgG水平，值得临床推广应用。
目的：探討人免疫毬蛋白輔助治療小兒重癥肺炎的臨床效果。方法選取本院2013年6月~2014年11月收治的80例小兒重癥肺炎患者作為研究對象，隨機分成觀察組和對照組，各40例。對照組採用常規治療，包括抗生素治療、抗病毒治療、吸氧以及糾正患者心力衰竭等。觀察組在對照組的基礎上給予人免疫毬蛋白輔助治療，比較兩組的治療效果。結果觀察組的治療總有效率顯著高于對照組，差異有統計學意義(P<0.05)。觀察組患者的退熱時間、咳嗽消失時間、啰音消失時間、X線胸片檢查炎癥吸收時間以及總住院時間顯著短于對照組，差異有統計學意義(P<0.05)。觀察組治療後的IgG水平顯著低于對照組，差異有統計學意義(P<0.05)。結論人免疫毬蛋白輔助治療小兒重癥肺炎效果顯著，能夠有效縮短退熱時間、咳嗽消失時間、啰音消失時間、X線胸片檢查炎癥吸收時間以及總住院時間，降低患者血清中的IgG水平，值得臨床推廣應用。
목적：탐토인면역구단백보조치료소인중증폐염적림상효과。방법선취본원2013년6월~2014년11월수치적80례소인중증폐염환자작위연구대상，수궤분성관찰조화대조조，각40례。대조조채용상규치료，포괄항생소치료、항병독치료、흡양이급규정환자심력쇠갈등。관찰조재대조조적기출상급여인면역구단백보조치료，비교량조적치료효과。결과관찰조적치료총유효솔현저고우대조조，차이유통계학의의(P<0.05)。관찰조환자적퇴열시간、해수소실시간、라음소실시간、X선흉편검사염증흡수시간이급총주원시간현저단우대조조，차이유통계학의의(P<0.05)。관찰조치료후적IgG수평현저저우대조조，차이유통계학의의(P<0.05)。결론인면역구단백보조치료소인중증폐염효과현저，능구유효축단퇴열시간、해수소실시간、라음소실시간、X선흉편검사염증흡수시간이급총주원시간，강저환자혈청중적IgG수평，치득림상추엄응용。
Objective To explore the clinical efficacy of human immunoglobulin as an adjuvant therapy in the treat-ment of pediatric severe peumonia. Methods 80 children with severe pneumonia from June 2013 to November 2014 in our hospital were selected and randomly divided into the control group and the observation group,40 cases in each group.The control group was treated with conventional treatment including antibiotics,anti-virus,oxygen inhalation and heart failure correcting,the observation group was given human immunoglobulin as an adjuvant therapy on the basis of control group.The therapeutic effect in two groups was compared. Results The total effective rate in the observation group was higher than that in the control group,with significant difference (P<0.05).The time of fever subsidence,cough disappeared time,rales disappear time,X-ray examination inflammation absorption time and the total hospitalization time in the observation group was shorter than that in the control group,with significant difference (P<0.05).The level of serum IgG after treatment in the observation group was lower than that in the control group,with significant difference (P<0.05). Conclusion The effect of human immunoglobulin as an adjuvant therapy in the treatment of pediatric severe pneumonia is significant,which can effectively shorten the time of fever subsidence,cough disappeared time,rales disap-pear time,X-ray examination inflammation absorption time and the total hospitalization time,reduce serum IgG level,it is worthy of clinical promotion and application.
