CAJ | 학술논문

目的：探讨哌拉西林舒巴坦联合左氧氟沙星治疗老年肺炎患者的临床效果。方法选取我院2012年9月至2014年12月呼吸内科99例老年肺炎患者进行药物治疗效果研究，采取不同的药物治疗方案将患者随机分为三组，研究组患者采取哌拉西林舒巴坦联合左氧氟沙星治疗，对照组1所有患者均应用哌拉西林舒巴坦治疗，对照组2采取左氧氟沙星治疗，观察对比三组患者疗效与不良反应率。结果患者经治疗后，研究组治疗总有效率为96．97％，对照组1为72．73％，对照组2为75．76％，研究组总有效率明显高于对照组1与2，两组数据差异具有统计学意义（P＜0．05）；研究组总不良反应率为6．06％，对照组1为3．03％，对照组2为3．03％，研究组总不良反应率与对照组1与2相近，P＞0．05，无统计学差异；对照组1与2总有效率与总不良反应率对比，P＞0．05，无统计学差异。结论研究结果显示老年肺炎患者采取哌拉西林舒巴坦联合左氧氟沙星治疗临床效果显著，且不良反应少，安全性高，具有极高的临床应用及推广价值。
목적：탐토고랍서림서파탄연합좌양불사성치료노년폐염환자적림상효과。방법선취아원2012년9월지2014년12월호흡내과99례노년폐염환자진행약물치료효과연구，채취불동적약물치료방안장환자수궤분위삼조，연구조환자채취고랍서림서파탄연합좌양불사성치료，대조조1소유환자균응용고랍서림서파탄치료，대조조2채취좌양불사성치료，관찰대비삼조환자료효여불량반응솔。결과환자경치료후，연구조치료총유효솔위96．97％，대조조1위72．73％，대조조2위75．76％，연구조총유효솔명현고우대조조1여2，량조수거차이구유통계학의의（P＜0．05）；연구조총불량반응솔위6．06％，대조조1위3．03％，대조조2위3．03％，연구조총불량반응솔여대조조1여2상근，P＞0．05，무통계학차이；대조조1여2총유효솔여총불량반응솔대비，P＞0．05，무통계학차이。결론연구결과현시노년폐염환자채취고랍서림서파탄연합좌양불사성치료림상효과현저，차불량반응소，안전성고，구유겁고적림상응용급추엄개치。
Objective To discuss the clinical effect of piperacillin sulbactam combined with levofloxacin in the treatment of elderly patients with pneumonia.Methods Selected from September 2012 to December 2014 99 cases of respiratory medicine study on effect of drug treatment in elderly patients with pneumonia, took different drug treatments, patients were randomly divided into three groups, Group A took piperacillin sulbactam combined with levofloxacin therapy, all patients in the control group got application of piperacillin sulbactam treatment, control group took levofloxacin therapy, observed and compared the efficacy and adverse reaction rates of three groups.Results Patients after treatment, the treatment group total effective rate was 96.97%, control group 1 was 72.73%, the control group was 75.76%, 2 group total effective rate was significantly higher than the control group 1 and 2, the data statistically significant differences in the two groups ( P <0.05 ); Team total adverse reaction rate was 6.06%, control group 1 was 3.03%, the control group was 3.03%, 2 team total rate of adverse reaction similar to the control group 1 and 2, P>0.05, no statistical difference;Control group 1 and 2 total effective rate and total rate of adverse reactions to contrast, P >0.05, no statistical difference. Conclusions The results showed that elderly patients with pneumonia taking piperacillin sulbactam combined with levofloxacin therapy, which has significant clinical effect and less side effects and is safe, with a high clinical application and promotion value.