CAJ | 학술논문

目的：评估甲胎蛋白（ AFP）与标准化残肝体积比对原发性肝癌根治切除术后复发风险的临床价值。方法回顾2009-05～2014-09期间68例临床分期相同的行原发性肝癌根治切除术患者资料，根据随访1年有无复发进行临床分组，其中复发组32例，未复发组36例，比较两组间患者术后AFP均值与标准化残肝体积，分析AFP与标准化残肝体积比在评估原发性肝癌根治切除术后复发风险的临床应用价值。结果复发组和未复发组术后的AFP均值分别为（110.25±89.44）ng／ml和（70.71±54.32）ng／ml，标准化残肝体积分别为（371.59±27.35）ml／m2和（462.56±61.96）ml／m2。复发组的AFP与标准化残肝体积比均值为（0.29±0.22），高于未复发组（0.16±0.16）（P＜0.01）。结论 AFP与标准化残肝体积比在评估原发性肝癌根治切除术后复发风险中有一定的临床价值，当原发性肝癌根治切除术后1年内的AFP与标准化残肝体积比超过0.2时，复发风险较高。
목적：평고갑태단백（ AFP）여표준화잔간체적비대원발성간암근치절제술후복발풍험적림상개치。방법회고2009-05～2014-09기간68례림상분기상동적행원발성간암근치절제술환자자료，근거수방1년유무복발진행림상분조，기중복발조32례，미복발조36례，비교량조간환자술후AFP균치여표준화잔간체적，분석AFP여표준화잔간체적비재평고원발성간암근치절제술후복발풍험적림상응용개치。결과복발조화미복발조술후적AFP균치분별위（110.25±89.44）ng／ml화（70.71±54.32）ng／ml，표준화잔간체적분별위（371.59±27.35）ml／m2화（462.56±61.96）ml／m2。복발조적AFP여표준화잔간체적비균치위（0.29±0.22），고우미복발조（0.16±0.16）（P＜0.01）。결론 AFP여표준화잔간체적비재평고원발성간암근치절제술후복발풍험중유일정적림상개치，당원발성간암근치절제술후1년내적AFP여표준화잔간체적비초과0.2시，복발풍험교고。
Objective To evaluate the clinical value of the ratio of the alpha fetoprotein( AFP) and standard remnant liver volume in the recurrence risk of primary liver cancer after resection.Methods Sixty-eight patients′clinical data were retrospectively analyzed, who were given the primary liver cancer resection in our hospital from May 2009 to September 2014, with a follow-up of 1 year.They were divided into two groups according to whether the dis-ease reoccurred or not.The recurrence group contained 32 patients, and the non-recurrence group contained 36 pa-tients.The mean AFP and standard postoperative residual liver volume were compared between the two groups to eval-uate the clinical value of the ratio of the alpha fetoprotein( AFP) and standard remnant liver volume in the recurrence risk of primary liver cancer after the resection.Results The postoperative AFP was ( 110.25 ±89.44 ) ng/ml and (70.71 ±54.32)ng/ml respectively in the recurrence group and the non-recurrence group;The standard remnant liv-er volume was (371.59 ±27.35) ml/m2 and (462.56 ±61.96) ml/m2 respectively in the recurrence group and the non-recurrence group.The ratio of AFP to standard remnant liver volume of the recurrence group was ( 0.29 ± 0.22), which was significantly higher than that of the non-recurrence group(0.16 ±0.16)(P<0.01).Conclusion There is certain clinical value of the ratio of AFP to standard remnant liver volume in the recurrence risk of primary liver cancer after resection.When it exceeds 0.2, the recurrence risk of primary carcinoma of the liver after resection will be higher in 1 year.