海峡药学
海峽藥學
해협약학
Strait Pharmaceutical Journal
2015年
9期
233-235
,共3页
硫酸吗啡缓释%盐酸羟考酮缓释片%癌痛%最小成本分析
硫痠嗎啡緩釋%鹽痠羥攷酮緩釋片%癌痛%最小成本分析
류산마배완석%염산간고동완석편%암통%최소성본분석
Morphine sulfate sustained-release tablets%Oxycodone hydrochloride prolonged-release tablets%Cancer pain%Cost mini-mization analysis
目的：比较硫酸吗啡缓释片和盐酸羟考酮缓释片治疗癌痛的成本和效果，为合理用药提供参考。方法回顾性分析我院2012～2014年采用硫酸吗啡缓释片及盐酸羟考酮缓释片治疗癌痛的患者707例，按照不同的治疗方案进行分组，其中硫酸吗啡缓释片110例，盐酸羟考酮缓释片597例，统计两组疗效及费用，并运用最小成本法进行分析。结果硫酸吗啡缓释片组有效率是78.2％，盐酸羟考酮缓释片组有效率是71.9％，两组比较差异无统计学意义；硫酸吗啡缓释片组治疗药物总成本为513.05±170.24，盐酸羟考酮缓释片组治疗药物总成本为1142.60±130.66。两组比较差异有统计学意义（ P＜0.05）。结论两种治疗方案治疗癌痛的疗效均较好，从经济学角度看，硫酸吗啡缓释片治疗成本较小，为较佳治疗方案。
目的：比較硫痠嗎啡緩釋片和鹽痠羥攷酮緩釋片治療癌痛的成本和效果，為閤理用藥提供參攷。方法迴顧性分析我院2012～2014年採用硫痠嗎啡緩釋片及鹽痠羥攷酮緩釋片治療癌痛的患者707例，按照不同的治療方案進行分組，其中硫痠嗎啡緩釋片110例，鹽痠羥攷酮緩釋片597例，統計兩組療效及費用，併運用最小成本法進行分析。結果硫痠嗎啡緩釋片組有效率是78.2％，鹽痠羥攷酮緩釋片組有效率是71.9％，兩組比較差異無統計學意義；硫痠嗎啡緩釋片組治療藥物總成本為513.05±170.24，鹽痠羥攷酮緩釋片組治療藥物總成本為1142.60±130.66。兩組比較差異有統計學意義（ P＜0.05）。結論兩種治療方案治療癌痛的療效均較好，從經濟學角度看，硫痠嗎啡緩釋片治療成本較小，為較佳治療方案。
목적：비교류산마배완석편화염산간고동완석편치료암통적성본화효과，위합리용약제공삼고。방법회고성분석아원2012～2014년채용류산마배완석편급염산간고동완석편치료암통적환자707례，안조불동적치료방안진행분조，기중류산마배완석편110례，염산간고동완석편597례，통계량조료효급비용，병운용최소성본법진행분석。결과류산마배완석편조유효솔시78.2％，염산간고동완석편조유효솔시71.9％，량조비교차이무통계학의의；류산마배완석편조치료약물총성본위513.05±170.24，염산간고동완석편조치료약물총성본위1142.60±130.66。량조비교차이유통계학의의（ P＜0.05）。결론량충치료방안치료암통적료효균교호，종경제학각도간，류산마배완석편치료성본교소，위교가치료방안。
ABSTRACT:OBJECTIVE To compare the economic evaluation of the treatment of cancer pain by using morphine sulfate sustained-release tablets and oxycodone hydrochloride prolonged-release tablets.METHODS A retrospective analysis of the treatment of patients with cancer pain by using morphine sulfate sustained -release tablets and oxycodo-ne hydrochloride prolonged-release tablets in our hospital during January 2012 to December 2014 ,there were 110 ca-ses of patients by using morphine sulfate sustained-release tablets and 597 cases of patients by using oxycodone hydrochloride prolonged-release tablets , respectively , the effective rate and the pharmaceutical costs of two groups were counted up.RESULTS The effective rates of the treatment of cancer pain by using morphine sulfate sus-tained-release tablets and oxycodone hydrochloride prolonged-release tablets were 78.2% and 71.9%, separately , there was no statistical difference between them ( P>0.05 );the total costs of drugs used to treat the cancer pain were 513.05 ±170.24 Yuan and 1142.60 ±130.66 Yuan respectively.CONCLUSION There was no difference in the effective rate of treatment by using these two drugs ,compared them by using the cost minimization analysis ,the treatment of cancer pain by using morphine sulfate sustained-release tablets is characterized by low cost and more e-conomical efficiency.
