中国医药导刊
中國醫藥導刊
중국의약도간
Chinese Journal of Medical Guide
2015年
10期
973-975
,共3页
子宫内膜异位症%卵巢%临床病理特征%预后%相关性
子宮內膜異位癥%卵巢%臨床病理特徵%預後%相關性
자궁내막이위증%란소%림상병리특정%예후%상관성
Endometriosis%Clinicopathological features%Ovarian prognosis%Correlation
目的：探讨卵巢型子宫内膜异位症的临床病理特征与预后的相关性。方法：选取2013年6月～2014年6月期间在我院住院行腹腔镜手术、病理确诊的卵巢型子宫内膜异位症患者60例作为观察组，同期选择确珍为非子宫内膜异位症的卵巢良性肿瘤患者60例为对照组，两组都进行骨桥蛋白的免疫组化分析、病理特征与预后情况调查，并进行相关性分析。结果：观察组的组织学分型、疾病分期和分化程度与对照组对比差异有统计学意义(P＜0.05)。OPN在观察组中的阳性表达率分别为56.7%，在对照组中的阳性表达率分别为83.3%，对比差异都有统计学意义(P＜0.05)。观察组与对照组的1年生存率分别为96.7%和85.0%，观察组1年生存率明显高于对照组(P＜0.05)。Pearson直线相关分析显示卵巢型子宫内膜异位症患者的组织学分型、疾病分期、分化程度和OPN阳性表达与1年生存率呈现明显相关性(P＜0.05)。结论：卵巢型子宫内膜异位症的临床病理特征多表现为透明细胞肿瘤、FIGOⅠ期与高分化状态，OPN呈现相对低表达状况，预后生存率比较高，且临床病理特征与预后有一定的相关性。
目的：探討卵巢型子宮內膜異位癥的臨床病理特徵與預後的相關性。方法：選取2013年6月～2014年6月期間在我院住院行腹腔鏡手術、病理確診的卵巢型子宮內膜異位癥患者60例作為觀察組，同期選擇確珍為非子宮內膜異位癥的卵巢良性腫瘤患者60例為對照組，兩組都進行骨橋蛋白的免疫組化分析、病理特徵與預後情況調查，併進行相關性分析。結果：觀察組的組織學分型、疾病分期和分化程度與對照組對比差異有統計學意義(P＜0.05)。OPN在觀察組中的暘性錶達率分彆為56.7%，在對照組中的暘性錶達率分彆為83.3%，對比差異都有統計學意義(P＜0.05)。觀察組與對照組的1年生存率分彆為96.7%和85.0%，觀察組1年生存率明顯高于對照組(P＜0.05)。Pearson直線相關分析顯示卵巢型子宮內膜異位癥患者的組織學分型、疾病分期、分化程度和OPN暘性錶達與1年生存率呈現明顯相關性(P＜0.05)。結論：卵巢型子宮內膜異位癥的臨床病理特徵多錶現為透明細胞腫瘤、FIGOⅠ期與高分化狀態，OPN呈現相對低錶達狀況，預後生存率比較高，且臨床病理特徵與預後有一定的相關性。
목적：탐토란소형자궁내막이위증적림상병리특정여예후적상관성。방법：선취2013년6월～2014년6월기간재아원주원행복강경수술、병리학진적란소형자궁내막이위증환자60례작위관찰조，동기선택학진위비자궁내막이위증적란소량성종류환자60례위대조조，량조도진행골교단백적면역조화분석、병리특정여예후정황조사，병진행상관성분석。결과：관찰조적조직학분형、질병분기화분화정도여대조조대비차이유통계학의의(P＜0.05)。OPN재관찰조중적양성표체솔분별위56.7%，재대조조중적양성표체솔분별위83.3%，대비차이도유통계학의의(P＜0.05)。관찰조여대조조적1년생존솔분별위96.7%화85.0%，관찰조1년생존솔명현고우대조조(P＜0.05)。Pearson직선상관분석현시란소형자궁내막이위증환자적조직학분형、질병분기、분화정도화OPN양성표체여1년생존솔정현명현상관성(P＜0.05)。결론：란소형자궁내막이위증적림상병리특정다표현위투명세포종류、FIGOⅠ기여고분화상태，OPN정현상대저표체상황，예후생존솔비교고，차림상병리특정여예후유일정적상관성。
Objective: To investigate the correlation between clinicopathological features and prognosis in the ovarian endometriosis.Methods:From June 2013 to June 2014 in our hospital,selected 60 ovarian endometriosis patients with pathologically confirmed as the observation group,and selected non endometriosis benign ovarian disease 60 patient as the control group, two groups were carried osteopontin immunohistochemical analysis and pathological features and prognosis surveys,and were given the correlation analysis.Results:The histological type,staging and differentiation compared the difference in the two groups were statistically significant difference (P<0.05).The OPN positive expression rates in the observation group and the control group were 56.7 % and 83.3% respectively that compared to the differences were statistically significant (P<0.05).The 1-year survival rates in the observation group and the control group were 96.7% and 85.0% that the 1 year survival rate of the observation group was significantly higher (P<0.05).Pearson linear correlation analysis showed that the ovarian endometriosis patients with histological type,stage of disease,differentiation and expression of OPN and 1-year survival rates were showed significant correlation (P<0.05).Conclusion:The ovarian endometriosis clinicopathological features is more performance for clear cell tumors,FIGOⅠ and scores state,OPN exhibit relatively low expression levels,the prognosis is relatively high survival rate,and the clinical pathological features is correlated to the prognosis.
