现代肿瘤医学
現代腫瘤醫學
현대종류의학
Journal of Modern Oncology
2015年
23期
3515-3517,3518
,共4页
肿瘤患者%手术切口感染%病原菌%耐药性
腫瘤患者%手術切口感染%病原菌%耐藥性
종류환자%수술절구감염%병원균%내약성
tumor patients%surgical incision infection%pathogenic distribution%drug resistance
目的：分析肿瘤患者手术切口感染病原菌的分布及耐药性，为临床合理使用抗生素提供依据。方法：回顾性分析2005年1月至2014年6月接受手术治疗的肿瘤患者发生切口感染的标本537例，病原菌的培养采用法国生物梅里埃公司 VITEK -2 Compact 全自动细菌鉴定药敏分析系统及其相应的配套试剂进行病原菌的鉴定以及药敏试验，分析其病原菌的分布及耐药率，采用 SPSS 17.0软件进行分析。结果：肿瘤患者手术感染病原菌中排名前3位的分别为大肠埃希菌81株占15.08％、铜绿假单胞菌77株占14.34％、金黄色葡萄球菌69株占12.85％。大肠埃希菌对氨曲南耐药率最高为72.84％、对亚胺培南耐药率最低为0；铜绿假单胞菌对氨苄西林/舒巴坦耐药率最高为79.22％、对亚胺培南耐药率最低为5.19％；金黄色葡萄球菌对克林霉素耐药率最高为76.81％、而对万古霉素和利奈唑胺的耐药率均为0。结论：临床要重视肿瘤患者这一特殊人群手术切口病原菌的分布及耐药性的变化，根据药敏结果使用抗生素，减少耐药菌的产生。
目的：分析腫瘤患者手術切口感染病原菌的分佈及耐藥性，為臨床閤理使用抗生素提供依據。方法：迴顧性分析2005年1月至2014年6月接受手術治療的腫瘤患者髮生切口感染的標本537例，病原菌的培養採用法國生物梅裏埃公司 VITEK -2 Compact 全自動細菌鑒定藥敏分析繫統及其相應的配套試劑進行病原菌的鑒定以及藥敏試驗，分析其病原菌的分佈及耐藥率，採用 SPSS 17.0軟件進行分析。結果：腫瘤患者手術感染病原菌中排名前3位的分彆為大腸埃希菌81株佔15.08％、銅綠假單胞菌77株佔14.34％、金黃色葡萄毬菌69株佔12.85％。大腸埃希菌對氨麯南耐藥率最高為72.84％、對亞胺培南耐藥率最低為0；銅綠假單胞菌對氨芐西林/舒巴坦耐藥率最高為79.22％、對亞胺培南耐藥率最低為5.19％；金黃色葡萄毬菌對剋林黴素耐藥率最高為76.81％、而對萬古黴素和利奈唑胺的耐藥率均為0。結論：臨床要重視腫瘤患者這一特殊人群手術切口病原菌的分佈及耐藥性的變化，根據藥敏結果使用抗生素，減少耐藥菌的產生。
목적：분석종류환자수술절구감염병원균적분포급내약성，위림상합리사용항생소제공의거。방법：회고성분석2005년1월지2014년6월접수수술치료적종류환자발생절구감염적표본537례，병원균적배양채용법국생물매리애공사 VITEK -2 Compact 전자동세균감정약민분석계통급기상응적배투시제진행병원균적감정이급약민시험，분석기병원균적분포급내약솔，채용 SPSS 17.0연건진행분석。결과：종류환자수술감염병원균중배명전3위적분별위대장애희균81주점15.08％、동록가단포균77주점14.34％、금황색포도구균69주점12.85％。대장애희균대안곡남내약솔최고위72.84％、대아알배남내약솔최저위0；동록가단포균대안변서림/서파탄내약솔최고위79.22％、대아알배남내약솔최저위5.19％；금황색포도구균대극림매소내약솔최고위76.81％、이대만고매소화리내서알적내약솔균위0。결론：림상요중시종류환자저일특수인군수술절구병원균적분포급내약성적변화，근거약민결과사용항생소，감소내약균적산생。
Objective:To study the distribution and drug resistance of the pathogenic bacteria in tumor patients. Methods:415 tumor patients with surgical wound infection were retrospectively evaluated VITEK - 32 fully automatic expression and original reagent were adopted for bacterial culture,bacteria identification and antimicrobial susceptibil-ity tests. Results:The top three pathogens of the tumor patients with surgical wound infection were escherichia coli with 81 strains(15. 08% ),pseudomonas aeruginosa with 77 strains(14. 34% )and staphylococcus aureus with 69 strains(12. 85% ). To Aztreonam,the escherichia coli had the highest drug resistance rate which was 72. 84% ,to imi-penem,the escherichia coli had the the lowest drug resistance rate which was 0. To ampicillin,the pseudomonas aerug-inosa had the the highest drug resistance rate which was 79. 22% ,to imipenem,the escherichia coli had the the lowest drug resistance rate which was 5. 19% . To clindamycin,the staphylococcus aureus had the the highest drug resistance rate which was 76. 81% ,to Vancomycin and imipenem,the staphylococcus aureus had the lowest drug resistance rate which was 0. Conclusion:The clinical should pay attention to the pathogenic bacteria distribution and drug resistance of surgical incision of tumor patients. The use of antibiotics should be based on susceptibility results,to reduce the bacterial resistance.
