CAJ | 학술논문

目的：对不明原因转移瘤患者，探讨利用正电子发射计算机断层显像（positron emission tomography/computed tomography，PET/ CT）寻找肿瘤原发灶的临床价值。方法：回顾性收集经病理学证实或影像学检查诊断为转移瘤的137例住院患者的临床及 PET/ CT 成像资料，计算全身 PET/ CT 显像对不明原因转移瘤患者肿瘤原发灶的检出率，分析不同部位转移瘤原发灶检出率间的差异。结果：确诊1例淋巴瘤患者被排除，18 F -FDG PET/ CT 正确检出原发病灶89例，检出率为65.4％（89/136）。18 F - FDG PET/ CT 对于淋巴结转移、骨转移、肝转移及脑转移瘤肿瘤原发灶检出率分别为63.2％（36/57）、60.0％（18/30）、86.7％（13/15）和57.1％（8/14）。结论：全身 PET/ CT 显像在不明原因转移瘤寻找肿瘤原发灶方面具有重要临床应用价值。
목적：대불명원인전이류환자，탐토이용정전자발사계산궤단층현상（positron emission tomography/computed tomography，PET/ CT）심조종류원발조적림상개치。방법：회고성수집경병이학증실혹영상학검사진단위전이류적137례주원환자적림상급 PET/ CT 성상자료，계산전신 PET/ CT 현상대불명원인전이류환자종류원발조적검출솔，분석불동부위전이류원발조검출솔간적차이。결과：학진1례림파류환자피배제，18 F -FDG PET/ CT 정학검출원발병조89례，검출솔위65.4％（89/136）。18 F - FDG PET/ CT 대우림파결전이、골전이、간전이급뇌전이류종류원발조검출솔분별위63.2％（36/57）、60.0％（18/30）、86.7％（13/15）화57.1％（8/14）。결론：전신 PET/ CT 현상재불명원인전이류심조종류원발조방면구유중요림상응용개치。
Objective:To explore the value of whole body PET/ CT scan with(18)F - fluorodeoxy glucose(FDG) in the diagnosis of metastatic carcinoma of unknown primary origin(CUP). Methods:A retrospective study was per-formed in patients diagnosed of metastatic carcinoma with CUP. All patients were confirmed by pathology or diagnostic imaging examinations. The recruited patients were received whole body 18 F - FDG PET - CT scan. Histopathological findings were used to determine the diagnostic value of 18 F - FDG PET - CT. Results:Total of 136 patients were in-cluded in the study. The primary tumor site was accurately identified by 18 F - FDG PET/ CT in 89 patients(89 / 136, 65. 4% ). The detection rate of the primary tumor site for metastatic lymph node carcinoma,bone metastasis,liver me-tastasis and brain metastasis were 63. 2%(36 / 57),60%(18 / 30),86. 7%(13 / 15)and 57. 1%(8 / 14)respective-ly. Conclusion:Whole body 18 F - FDG PET/ CT has important clinical value in detecting primary site of CUP.