现代肿瘤医学
現代腫瘤醫學
현대종류의학
Journal of Modern Oncology
2015年
23期
3528-3530,3531
,共4页
脑转移瘤%发生机制%血脑屏障
腦轉移瘤%髮生機製%血腦屏障
뇌전이류%발생궤제%혈뇌병장
brain metastases%mechanism%blood - brain barrier
在恶性肿瘤发展的过程中，发生脑转移瘤的概率可达20％～40％，且正在上升。未经治疗的脑转移瘤有着极差的预后，因此，进一步了解其发生机制，并以此为基础优化治疗方案十分重要。本文将对脑转移瘤的形成机制做一综述。
在噁性腫瘤髮展的過程中，髮生腦轉移瘤的概率可達20％～40％，且正在上升。未經治療的腦轉移瘤有著極差的預後，因此，進一步瞭解其髮生機製，併以此為基礎優化治療方案十分重要。本文將對腦轉移瘤的形成機製做一綜述。
재악성종류발전적과정중，발생뇌전이류적개솔가체20％～40％，차정재상승。미경치료적뇌전이류유착겁차적예후，인차，진일보료해기발생궤제，병이차위기출우화치료방안십분중요。본문장대뇌전이류적형성궤제주일종술。
In the process of the development of malignant tumor,incidence of brain metastases is up to 20% ~ 40% . Brain metastases are the most common intracranial tumors and their incidence is increasing. Untreated brain metasta-ses has a poor prognosis and a poor performance status. So,further understanding of the mechanism,and on this basis, optimizing the treatment is very important. The advent of new technologies has led to the discovery of novel molecules and pathways that have better depicted the metastatic process. In this paper,we will briefly review recent research progress in mechanism of brain metastases.
