CAJ | 학술논문

目的：探讨泵入利尿剂改善慢性肾小球肾炎水肿症状的疗效。方法：选择2011年7月～2014年2月在我院住院治疗的慢性肾小球肾炎患者172例，根据随机抽签原则分为治疗组86例与对照组86例，对照组给予常规综合治疗，治疗组在对照组治疗的基础上给予泵入利尿剂进行治疗，两组治疗观察时间为3个月。结果：治疗后治疗组与对照组的总有效率分别为97.7%和84.9%，治疗组高于对照组(P＜0.05)。治疗后治疗组与对照组的尿蛋白定量为（0.88±0.23）g/24h和（1.09±0.49）g/24h，都明显低于治疗前的（1.33±0.45）g/24h和（1.35±0.38）g/24h(P＜0.05)，组间对比差异具有统计学意义(P＜0.05)。治疗后治疗组与对照组的水肿症状评分分别为（0.98±0.45）分和（1.89±0.32）分(P＜0.05)，都明显低于治疗前的（4.56±0.56）分和（4.61±0.44）分，同时组间对比差异也有统计学意义(P＜0.05)。两组治疗后的血肌酐含量都明显低于治疗前(P＜0.05)，同时治疗后组间对比差异明显(P＜0.05)。结论：泵入利尿剂治疗能有效改善慢性肾小球肾炎患者的水肿症状，增加尿蛋白定量，促进肾功能的恢复，从而提高总体治疗疗效。
목적：탐토빙입이뇨제개선만성신소구신염수종증상적료효。방법：선택2011년7월～2014년2월재아원주원치료적만성신소구신염환자172례，근거수궤추첨원칙분위치료조86례여대조조86례，대조조급여상규종합치료，치료조재대조조치료적기출상급여빙입이뇨제진행치료，량조치료관찰시간위3개월。결과：치료후치료조여대조조적총유효솔분별위97.7%화84.9%，치료조고우대조조(P＜0.05)。치료후치료조여대조조적뇨단백정량위（0.88±0.23）g/24h화（1.09±0.49）g/24h，도명현저우치료전적（1.33±0.45）g/24h화（1.35±0.38）g/24h(P＜0.05)，조간대비차이구유통계학의의(P＜0.05)。치료후치료조여대조조적수종증상평분분별위（0.98±0.45）분화（1.89±0.32）분(P＜0.05)，도명현저우치료전적（4.56±0.56）분화（4.61±0.44）분，동시조간대비차이야유통계학의의(P＜0.05)。량조치료후적혈기항함량도명현저우치료전(P＜0.05)，동시치료후조간대비차이명현(P＜0.05)。결론：빙입이뇨제치료능유효개선만성신소구신염환자적수종증상，증가뇨단백정량，촉진신공능적회복，종이제고총체치료료효。
Objective: To investigate the diuretic pumped into improving chronic glomerulonephritis symptoms of edema effect. Methods:July 2011 to February 2014 in our hospital treated 172 cases of patients with chronic glomerulonephritis,according to the principle of random draw into the treatment group of 86 patients and the control group of 86 patients in the control group received conventional treatment,The treatment group received the pump on the basis of the control group on the diuretic treatment,and after treatment observation period of 3 months.Results:After treatment,the treatment group and the control group,an efficiency of 97.7% and 84.9% respectively,the total effective rate was significantly higher (P<0.05) treatment groups.Urinary protein treatment group and the control group was (0.88±0.23)g/24h and (1.09±0.49)g/24h,were significantly lower than before treatment (1.33±0.45)g/24h and (1.35± 0.38)g/24h (P<0.05),compared to differences between the two groups was statistically significant (P<0.05).The treatment group and the control group edema symptom score was (0.98±0.45)and (1.89±0.32) points points (P<0.05),were significantly lower than before treatment of (4.56±0.56) points and (4.61±0.44) points,compared to between-group differences at the same time there was statistically significant (P<0.05).After treatment,serum creatinine content were significantly lower than before treatment (P<0.05),while serum creatinine content after treatment treatment group was significantly lower than the control group (P<0.05).Conclusion:The pumped into diuretic therapy can improve symptoms of edema in patients with chronic glomerulonephritis,increased urinary protein excretion,and promote the recovery of renal function,and thereby improve overall treatment efficacy.