CAJ | 학술논문

目的：分析地佐辛复合舒芬太尼用于胃癌根治术术后镇痛的临床效果。方法：选取2013年7月～2015年7月在本院接受胃癌根治术的患者110例作为研究对象，根据术后镇痛方式不同，将所有入组患者随机分为观察组及对照组各55例。对照组患者接受单纯舒芬太尼镇痛，观察组患者接受地佐辛复合舒芬太尼镇痛，对比两组患者的术后疼痛及镇静评分、血清炎症因子水平等差异。结果：观察组患者的治疗后 VAS 评分值低于对照组、Ramsay 评分值高于对照组患者，差异有统计学意义（P ＜0.05）；观察组患者接受治疗后的血清 CRP、IL －6、IL －8、PCT 水平均低于对照组患者，差异有统计学意义（P ＜0.05）。结论：胃癌根治术患者接受地佐辛复合舒芬太尼镇痛，可以有效减轻疼痛并提升镇静程度，降低全身炎症状态，具有积极的临床意义。
목적：분석지좌신복합서분태니용우위암근치술술후진통적림상효과。방법：선취2013년7월～2015년7월재본원접수위암근치술적환자110례작위연구대상，근거술후진통방식불동，장소유입조환자수궤분위관찰조급대조조각55례。대조조환자접수단순서분태니진통，관찰조환자접수지좌신복합서분태니진통，대비량조환자적술후동통급진정평분、혈청염증인자수평등차이。결과：관찰조환자적치료후 VAS 평분치저우대조조、Ramsay 평분치고우대조조환자，차이유통계학의의（P ＜0.05）；관찰조환자접수치료후적혈청 CRP、IL －6、IL －8、PCT 수평균저우대조조환자，차이유통계학의의（P ＜0.05）。결론：위암근치술환자접수지좌신복합서분태니진통，가이유효감경동통병제승진정정도，강저전신염증상태，구유적겁적림상의의。
Objective: To analyze the effect of dezocine combined with sufentanil on gastric cancer patients 'postoperative analgesia.Methods:110 cases of gastric cancer patients between July 2013 to July 2015 in our hospital were choosed as research sub-jects and randomly divided into observation group (n =55)and control group (n =55)according to different postoperative analgesia ways.Control group patients received sufentanil analgesia alone,observation group patients received Dezocine combined with sufentanil analgesia,compared two group patients'postoperative pain and sedation scores,serum levels of inflammatory cytokines.Results:Ob-servation group patients VAS score was lower than control group patients after treatment,Ramsay score was higher than control group patients,the difference was statistically significant (P <0.05);observation group patients serum CRP,IL -6,IL -8,PCT levels after treatment were lower than control group patients,the difference was statistically significant (P <0.05).Conclusion:Gastric cancer patients receive Dezocine combined with sufentanil analgesia can effectively reduce pain and improve sedation,reduce the sys-temic inflammatory state,has a positive significance.