中国药业
中國藥業
중국약업
China Pharmaceuticals
2015年
19期
78-79
,共2页
张婷%别玉坤%王国辉%冯以斌
張婷%彆玉坤%王國輝%馮以斌
장정%별옥곤%왕국휘%풍이빈
混合糖电解质注射液%肝胆外科%血糖%炎症反应%术中配合
混閤糖電解質註射液%肝膽外科%血糖%炎癥反應%術中配閤
혼합당전해질주사액%간담외과%혈당%염증반응%술중배합
mixed sugar electrolyte injection%liver and gallbladder surgery%blood glucose%inflammatory reaction%nursing
目的：观察混合糖电解质注射液用于肝胆手术后补液及对血糖、炎症反应的影响。方法选取行择期肝胆手术患者76例，随机分为对照组和观察组，各38例。对照组患者予以10%葡萄糖注射液联合10%氯化钾注射液及10%氯化钠注射液进行术后补液，观察组患者予以混合电解质注射液治疗。结果治疗第1天，两组患者血糖水平较前均明显升高（ P﹤0.05），但组间未见明显差异（ P﹥0.05）；治疗第3天，两组患者血糖水平较治疗第1天均有所下降，但仅观察组有统计学差异（ P﹤0.05）。两组患者术后C反应蛋白（CRP）、白细胞介素－6（IL－6）及肿瘤坏死因子－α（TNF－α）水平较前均有明显上升（ P﹤0.05）；治疗第3天，观察组患者CRP及TNF－α较对照组明显下降（ P﹤0.05）。对照组患者全身炎症反应综合征( SIRS )发生率显著高于观察组患者（ P﹤0.05）。两组患者不良反应发生情况比较无明显差异（ P﹥0.05）。结论混合糖电解质注射液用于肝胆术后患者补液安全、有效，可临床推广。
目的：觀察混閤糖電解質註射液用于肝膽手術後補液及對血糖、炎癥反應的影響。方法選取行擇期肝膽手術患者76例，隨機分為對照組和觀察組，各38例。對照組患者予以10%葡萄糖註射液聯閤10%氯化鉀註射液及10%氯化鈉註射液進行術後補液，觀察組患者予以混閤電解質註射液治療。結果治療第1天，兩組患者血糖水平較前均明顯升高（ P﹤0.05），但組間未見明顯差異（ P﹥0.05）；治療第3天，兩組患者血糖水平較治療第1天均有所下降，但僅觀察組有統計學差異（ P﹤0.05）。兩組患者術後C反應蛋白（CRP）、白細胞介素－6（IL－6）及腫瘤壞死因子－α（TNF－α）水平較前均有明顯上升（ P﹤0.05）；治療第3天，觀察組患者CRP及TNF－α較對照組明顯下降（ P﹤0.05）。對照組患者全身炎癥反應綜閤徵( SIRS )髮生率顯著高于觀察組患者（ P﹤0.05）。兩組患者不良反應髮生情況比較無明顯差異（ P﹥0.05）。結論混閤糖電解質註射液用于肝膽術後患者補液安全、有效，可臨床推廣。
목적：관찰혼합당전해질주사액용우간담수술후보액급대혈당、염증반응적영향。방법선취행택기간담수술환자76례，수궤분위대조조화관찰조，각38례。대조조환자여이10%포도당주사액연합10%록화갑주사액급10%록화납주사액진행술후보액，관찰조환자여이혼합전해질주사액치료。결과치료제1천，량조환자혈당수평교전균명현승고（ P﹤0.05），단조간미견명현차이（ P﹥0.05）；치료제3천，량조환자혈당수평교치료제1천균유소하강，단부관찰조유통계학차이（ P﹤0.05）。량조환자술후C반응단백（CRP）、백세포개소－6（IL－6）급종류배사인자－α（TNF－α）수평교전균유명현상승（ P﹤0.05）；치료제3천，관찰조환자CRP급TNF－α교대조조명현하강（ P﹤0.05）。대조조환자전신염증반응종합정( SIRS )발생솔현저고우관찰조환자（ P﹤0.05）。량조환자불량반응발생정황비교무명현차이（ P﹥0.05）。결론혼합당전해질주사액용우간담술후환자보액안전、유효，가림상추엄。
Objective To observe the influence of mixed glucose electrolyte injection on blood glucose and inflammatory reaction after hepatobiliary surgery. Methods :76 cases of patients undergoing hepatobiliary surgery were selected and randomly divided into control group and observation group, 38 cases in each group. The control group was treated with 10% glucose injection combined with 10%KCl and 10%NaCl, and the observation group was treated with mixed electrolyte injection. Results On the first day of treatment, the blood glucose levels of the two groups were significantly higher than before ( P ﹤ 0. 05 ) , but there was no significant difference between the groups ( P ﹥ 0. 05 ) . On the third day of treatment, the blood glucose levels of the two groups decreased, but only the decrease in the observation group was with significant difference ( P ﹤ 0. 05 ) . The CRP, IL-6 and TNF-α of the two groups were significantly in-creased after treatment ( P ﹤ 0. 05 ) , and the CRP and TNF-α in the observation group were significantly lower than those in the con-trol group on the third day of treatment ( P ﹤ 0. 05 ) . The incidence rate of SIRS in the control group was significantly higher than that in the observation group ( P ﹤ 0. 05 ) . There was no significant difference in the incidence of adverse reactions between the two groups ( P ﹥ 0. 05 ) . Conclusion The treatment mixed sugar electrolyte injection after hepatobiliary surgery is safe and effective, and is worthy of clinical promotion.
