国际眼科杂志
國際眼科雜誌
국제안과잡지
International Eye Science
2015年
11期
1905-1908
,共4页
趋化因子受体7%胞外信号调节激酶%血管内皮生长因子%视网膜新生血管
趨化因子受體7%胞外信號調節激酶%血管內皮生長因子%視網膜新生血管
추화인자수체7%포외신호조절격매%혈관내피생장인자%시망막신생혈관
C - C chemokine receptor type 7%extracellular signal regulate kinase%vascular endothelial growth factor%retinal neovascularization
视网膜新生血管性疾病是致盲的主要原因。趋化因子受体7( C-C chemokine receptor type 7, CCR7)可通过细胞外信号调节激酶( extracellular signal regulate kinase,ERK)通路促进血管内皮生长因子( vascular endothelial growth factor, VEGF)的表达,导致血管渗漏、血管内皮细胞增生以及新生血管形成等改变。趋化因子受体7的检测可指导视网膜新生血管性疾病的诊治。
視網膜新生血管性疾病是緻盲的主要原因。趨化因子受體7( C-C chemokine receptor type 7, CCR7)可通過細胞外信號調節激酶( extracellular signal regulate kinase,ERK)通路促進血管內皮生長因子( vascular endothelial growth factor, VEGF)的錶達,導緻血管滲漏、血管內皮細胞增生以及新生血管形成等改變。趨化因子受體7的檢測可指導視網膜新生血管性疾病的診治。
시망막신생혈관성질병시치맹적주요원인。추화인자수체7( C-C chemokine receptor type 7, CCR7)가통과세포외신호조절격매( extracellular signal regulate kinase,ERK)통로촉진혈관내피생장인자( vascular endothelial growth factor, VEGF)적표체,도치혈관삼루、혈관내피세포증생이급신생혈관형성등개변。추화인자수체7적검측가지도시망막신생혈관성질병적진치。
Retinal neovascularization diseases are the major causes of blindness. C-C chemokine receptor type 7 (CCR7) can promote the expression of vascular endothelial growth factor ( VEGF ) through the extracellular signal regulated kinase ( ERK ) pathway, leading to vascular leakage, proliferation of vascular endothelial neovascularization and etc. The detection of CCR7 can guide the diagnosis and treatments of retinal neovascularization diseases. cell neovascularization and etc. The detection of CCR7 can guide the diagnosis and treatments of retinal neovascularization diseases.
