国际眼科杂志
國際眼科雜誌
국제안과잡지
International Eye Science
2015年
11期
2003-2005
,共3页
糖尿病视网膜病变%胱抑素C%血脂改变%相关性
糖尿病視網膜病變%胱抑素C%血脂改變%相關性
당뇨병시망막병변%광억소C%혈지개변%상관성
diabetic retinopathy%Cys C%blood lipid change%correlation
目的：：探讨糖尿病视网膜病变( diabetic retinopathy, DR)患者胱抑素C、血脂水平及相关性。方法：选取2011-06/2014-12 DR患者60例为研究对象。根据DR国际分期无明显视网膜病变的28例,轻、中、重非增生性视网膜病变22例,增生性糖尿病视网膜病变10例。选择60例糖尿病无视网膜病变患者为疾病对照组( NDR组)；选择60例健康者为健康对照组。检测受试者胱抑素C、甘油三酯及总胆固醇水平。结果：DR组胱抑素 C、甘油三酯及总胆固醇水平高于NDR组和健康对照组,而NDR组高于健康对照组,差异有统计学意义(P<0.05)；随着DR病变程度的加重,胱抑素 C水平呈增加趋势,差异有统计学意义(P<0.05)；胱抑素C与病程、血脂水平呈正相关(P<0.05)。结论：DR患者存在胱抑素C水平异常变化,且随着DR的进展,胱抑素C水平呈不断升高趋势。 DR患者胱抑素C水平的变化与血脂异常相关。
目的：：探討糖尿病視網膜病變( diabetic retinopathy, DR)患者胱抑素C、血脂水平及相關性。方法：選取2011-06/2014-12 DR患者60例為研究對象。根據DR國際分期無明顯視網膜病變的28例,輕、中、重非增生性視網膜病變22例,增生性糖尿病視網膜病變10例。選擇60例糖尿病無視網膜病變患者為疾病對照組( NDR組)；選擇60例健康者為健康對照組。檢測受試者胱抑素C、甘油三酯及總膽固醇水平。結果：DR組胱抑素 C、甘油三酯及總膽固醇水平高于NDR組和健康對照組,而NDR組高于健康對照組,差異有統計學意義(P<0.05)；隨著DR病變程度的加重,胱抑素 C水平呈增加趨勢,差異有統計學意義(P<0.05)；胱抑素C與病程、血脂水平呈正相關(P<0.05)。結論：DR患者存在胱抑素C水平異常變化,且隨著DR的進展,胱抑素C水平呈不斷升高趨勢。 DR患者胱抑素C水平的變化與血脂異常相關。
목적：：탐토당뇨병시망막병변( diabetic retinopathy, DR)환자광억소C、혈지수평급상관성。방법：선취2011-06/2014-12 DR환자60례위연구대상。근거DR국제분기무명현시망막병변적28례,경、중、중비증생성시망막병변22례,증생성당뇨병시망막병변10례。선택60례당뇨병무시망막병변환자위질병대조조( NDR조)；선택60례건강자위건강대조조。검측수시자광억소C、감유삼지급총담고순수평。결과：DR조광억소 C、감유삼지급총담고순수평고우NDR조화건강대조조,이NDR조고우건강대조조,차이유통계학의의(P<0.05)；수착DR병변정도적가중,광억소 C수평정증가추세,차이유통계학의의(P<0.05)；광억소C여병정、혈지수평정정상관(P<0.05)。결론：DR환자존재광억소C수평이상변화,차수착DR적진전,광억소C수평정불단승고추세。 DR환자광억소C수평적변화여혈지이상상관。
Abstract?AlM:To study the correlation of Cys C and blood lipid with diabetic retinopathy ( DR) .?METHODS:Sixty patients with DR from June 2011 to December 2014 were selected. According to international criteria, in the patients with DR, there were 28 cases without remarkable DR, 22 cases with mild, middle and sever nonproliferative diabetic retinopathy ( NPDR ) , 10 cases with proliferative diabetic retinopathy ( PDR ) . Sixty diabetic patients without DR were selected as NDR group. Sixty healthy people were selected as control group. Cys C, triglyceride ( TG) and total cholesterol ( TC) were detected.?RESULTS:ln DR group, Cys C, TG and TC levels were higher than those in the NDR group and the control group, while in NDR group Cys C, TG and TC levels were higher than thoes in the control group, and the difference was statistically significant (P< 0. 05). As DR aggravating, Cys C increased, and the difference was statistically significant (P<0. 05). Cys C were positively correlated with the duration and blood lipid level (P<0. 05).?CONCLUSlON:Cys C changes abnormally in patients with DR, and with the progress of DR, Cys C trends to increase. The abnormal changes in DR patients positively associated with dyslipidemia.
