CAJ | 학술논문

青霉素作为一种抗生素因对多数革兰阳性细菌和阴性球菌、放线菌、螺旋体等有强大的抗菌作用，其效果好、见效快，且价格低廉，因此被基层医院广泛应用。青霉素类药物容易导致过敏性休克，中国药典明确规定[1]，常见的过敏反应在各种药物中居首位，发生率最高可达5%~10%；青霉素过敏反应包括速发型及迟发型过敏反应。速发型过敏反应多在皮肤过敏试验数秒钟或数分钟内即出现过敏反应，有时甚至呈闪电式的反应；迟发型过敏性反应指少数患者在做青霉素过敏试验阴性后，使用青霉素24~48h后发生的过敏性反应。因此迟发型过敏性反应则容易被忽视。
청매소작위일충항생소인대다수혁란양성세균화음성구균、방선균、라선체등유강대적항균작용，기효과호、견효쾌，차개격저렴，인차피기층의원엄범응용。청매소류약물용역도치과민성휴극，중국약전명학규정[1]，상견적과민반응재각충약물중거수위，발생솔최고가체5%~10%；청매소과민반응포괄속발형급지발형과민반응。속발형과민반응다재피부과민시험수초종혹수분종내즉출현과민반응，유시심지정섬전식적반응；지발형과민성반응지소수환자재주청매소과민시험음성후，사용청매소24~48h후발생적과민성반응。인차지발형과민성반응칙용역피홀시。
Penicil in as an antibiotic for most gram-positive bacterium and negative bacteria, actinomyces, helix has strong antimicrobial ef ect, its ef ect is good, quick ef ect, and the price is low, so the basic-level hospitals widely used. Penicil in drugs is easy to cause anaphylactic shock, Chinese pharmacopoeia stipulates clearly [1], common kind of al ergic reaction among various kinds of drugs in the first place, the incidence of up to 5%~5%; Including speed hairstyle and late onset of being al ergic to penicil in al ergic reactions. Anaphylaxis skin al ergy test in more seconds or minutes namely appear al ergic reaction, sometimes even a whirlwind of response;Delayed-type hypersensitivity reaction to a few patients after penicil in al ergy test negative 24~48 h after the application of penicil in anaphylactic reaction.