CAJ | 학술논문

目的：研究舒肝宁治疗药物性肝炎的临床疗效。方法60例药物性肝炎患者，随机分为试验组与对照组，各30例。对照组使用硫普罗宁治疗，试验组在对照组的基础上使用舒肝宁治疗，比较两组患者肝功能改善情况。结果治疗前，两组患者丙氨酸转氨酶(ALT)、门冬氨酸转氨酶(AST)、总胆红素(TBIL)比较，差异无统计学意义(P>0.05)；治疗后，试验组ALT、AST、TBIL值均优于对照组，差异有统计学意义(P<0.05)。结论使用舒肝宁治疗药物性肝炎，可明显改善患者肝功能，提高临床疗效，值得在临床推广。
목적：연구서간저치료약물성간염적림상료효。방법60례약물성간염환자，수궤분위시험조여대조조，각30례。대조조사용류보라저치료，시험조재대조조적기출상사용서간저치료，비교량조환자간공능개선정황。결과치료전，량조환자병안산전안매(ALT)、문동안산전안매(AST)、총담홍소(TBIL)비교，차이무통계학의의(P>0.05)；치료후，시험조ALT、AST、TBIL치균우우대조조，차이유통계학의의(P<0.05)。결론사용서간저치료약물성간염，가명현개선환자간공능，제고림상료효，치득재림상추엄。
ObjectiveTo research clinical effect by Shuganning in the treatment of drug-induced hepatitis.MethodsA total of 60 patients with drug-induced hepatitis were randomly divided into experimental group and control group, with 30 cases in each group. The control group received tiopronin for treatment, and the experimental group received additional Shuganning. Improvements of liver function were compared between the two groups.ResultsThere was no statistically significant difference of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and total bilirubin (TBIL) between the two groups before treatment (P>0.05). After treatment, the experimental group had better ALT, AST, and TBIL than the control group, and their difference had statistical significance (P<0.05).ConclusionImplement of Shuganning in the treatment of drug-induced hepatitis can remarkably improve liver function and clinical effect for patients. It is worth clinical promotion.