中国现代药物应用
中國現代藥物應用
중국현대약물응용
Chinese Journal of Modern Drug Application
2015年
21期
18-19
,共2页
卡前列素氨丁三醇%产后出血%宫缩乏力
卡前列素氨丁三醇%產後齣血%宮縮乏力
잡전렬소안정삼순%산후출혈%궁축핍력
Carboprost tromethamine%Postpartum hemorrhage%Uterine inertia
目的：观察卡前列素氨丁三醇(安列克)防治产后出血的应用效果。方法120例由宫缩乏力引起有产后出血倾向的患者随机分为观察组与对照组，各60例。对照组采用催产素加卡孕栓预防产后出血，观察组采用安列克预防产后出血，比较两组产后出血率、不良反应情况及产后2、24 h 出血量。结果观察治疗产后出血率6.7%明显低于对照组25.0%，差异有统计学意义(P<0.05)；观察组产后2、24 h 出血量均低于对照组，差异有统计学意义(P<0.05)；两组孕产妇不良反应发生情况比较差异无统计学意义(P>0.05)。结论安列克是一种国产的安全、有效、价格适中的强有效子宫收缩剂，可有效减少产后出血量及子宫动脉栓塞术和子宫全切等子宫手术率，其治疗宫缩乏力性产后出血，效果显著，越早使用，效果越好。
目的：觀察卡前列素氨丁三醇(安列剋)防治產後齣血的應用效果。方法120例由宮縮乏力引起有產後齣血傾嚮的患者隨機分為觀察組與對照組，各60例。對照組採用催產素加卡孕栓預防產後齣血，觀察組採用安列剋預防產後齣血，比較兩組產後齣血率、不良反應情況及產後2、24 h 齣血量。結果觀察治療產後齣血率6.7%明顯低于對照組25.0%，差異有統計學意義(P<0.05)；觀察組產後2、24 h 齣血量均低于對照組，差異有統計學意義(P<0.05)；兩組孕產婦不良反應髮生情況比較差異無統計學意義(P>0.05)。結論安列剋是一種國產的安全、有效、價格適中的彊有效子宮收縮劑，可有效減少產後齣血量及子宮動脈栓塞術和子宮全切等子宮手術率，其治療宮縮乏力性產後齣血，效果顯著，越早使用，效果越好。
목적：관찰잡전렬소안정삼순(안렬극)방치산후출혈적응용효과。방법120례유궁축핍력인기유산후출혈경향적환자수궤분위관찰조여대조조，각60례。대조조채용최산소가잡잉전예방산후출혈，관찰조채용안렬극예방산후출혈，비교량조산후출혈솔、불량반응정황급산후2、24 h 출혈량。결과관찰치료산후출혈솔6.7%명현저우대조조25.0%，차이유통계학의의(P<0.05)；관찰조산후2、24 h 출혈량균저우대조조，차이유통계학의의(P<0.05)；량조잉산부불량반응발생정황비교차이무통계학의의(P>0.05)。결론안렬극시일충국산적안전、유효、개격괄중적강유효자궁수축제，가유효감소산후출혈량급자궁동맥전새술화자궁전절등자궁수술솔，기치료궁축핍력성산후출혈，효과현저，월조사용，효과월호。
ObjectiveTo observe application effect of carboprost tromethamine (Anlieke) in prevention and treatment of postpartum hemorrhage.MethodsA total of 120 uterine inertia patients with postpartum hemorrhage tendency were randomly divided into observation group and control group, with 60 cases in each group. The control group received oxytocin combined with carprost suppository for prevention of postpartum hemorrhage. The observation group received Anlieke for prevention of postpartum hemorrhage. Postpartum hemorrhage rate, adverse reactions and bleeding volume in postpartum 2, 24 h were compared between the two groups.ResultsThe observation group had much lower postpartum hemorrhage rate as 6.7% than 25.0% of the control group, and the difference had statistical significance (P<0.05). The observation group had lower bleeding volume in postpartum 2, 24 h than the control group, and the difference had statistical significance (P<0.05). There was no statistically significant difference of adverse reactions between the two groups (P>0.05).ConclusionAs a domestic hysterotonics with safety, effectiveness, and moderate value, Anlieke can effectively reduce postpartum bleeding volume, and operation rate of uterine arterial embolization and hysterectomy. Early implement of Anlieke can provide precise effect in treating postpartum hemorrhage caused by uterine inertia.
