CAJ | 학술논문

目的：观察β-七叶皂苷钠联合牵引与推拿治疗神经根型颈椎病的临床疗效。方法将108例确诊患者随机分为观察组62例和对照组46例。两组患者均予以牵引和推拿治疗，观察组患者在此基础上加用β-七叶皂苷钠。结果与对照组相比，观察组患者总有效率显著提高（P＜0．05）；两组患者治疗后疼痛指数较前均显著下降（P＜0．05），但组间未见明显差异（P＞0．05）；治疗后观察组血浆内皮素（ET）、血栓素B2（TXB2）含量均有下降趋势，且降幅大于对照组（P＜0．05）；观察组的6-酮-前列腺素F1（6-K-PGF1）水平呈上升趋势，与对照组比较，差异有统计学意义（P＜0．05）。两者不良反应发生情况比较，差异无统计学意义（P＞0．05）。结论应用β-七叶皂苷钠治疗神经根型颈椎病，能有效消除神经根及周围组织的炎症，改善微循环，安全性较好，值得推广。
목적：관찰β-칠협조감납연합견인여추나치료신경근형경추병적림상료효。방법장108례학진환자수궤분위관찰조62례화대조조46례。량조환자균여이견인화추나치료，관찰조환자재차기출상가용β-칠협조감납。결과여대조조상비，관찰조환자총유효솔현저제고（P＜0．05）；량조환자치료후동통지수교전균현저하강（P＜0．05），단조간미견명현차이（P＞0．05）；치료후관찰조혈장내피소（ET）、혈전소B2（TXB2）함량균유하강추세，차강폭대우대조조（P＜0．05）；관찰조적6-동-전렬선소F1（6-K-PGF1）수평정상승추세，여대조조비교，차이유통계학의의（P＜0．05）。량자불량반응발생정황비교，차이무통계학의의（P＞0．05）。결론응용β-칠협조감납치료신경근형경추병，능유효소제신경근급주위조직적염증，개선미순배，안전성교호，치득추엄。
Objective To investigate the clinical effect of sodium aescinate combined with traction and massage in treating cervical spondylotic radiculopathy.Methods Totally 108 patients were randomly divided into the observation group (62 case )and the control group (46 cases ).Two groups were given traction and massage therapy,on this basis,the observation group was added sodium aescinate. Results Compared with the control group,the total effective rate of the observation group increased significantly(P <0.05);after treat-ment,the pain index was significantly decreased in the two groups(P <0.05 ),but the difference between the two group has no significantly difference(P >0.05);after treatment,the ET and TXB2 levels were decreased in the two groups(P <0.05),and the ob-servation group decreased more significantly than the control group(P <0.05).The 6-K-PGF1 levels of the observation group signifi-cantly increased,and had significant difference compared with the control group(P <0.05).The occurrence rate of the adverse reac-tions had no significant difference between the two groups(P >0.05).Conclusion Sodium aescinate in treating cervical spondylotic radiculopathy can effectively eliminate the inflammation of the nerve root and surrounding tissue,improve the microcirculation.It is high-ly safe and is worthy of clinical promotion.