中国药业
中國藥業
중국약업
China Pharmaceuticals
2015年
20期
134-135
,共2页
标准桃金娘油肠溶胶囊%地塞米松%鼓室内注射%分泌性中耳炎
標準桃金孃油腸溶膠囊%地塞米鬆%鼓室內註射%分泌性中耳炎
표준도금낭유장용효낭%지새미송%고실내주사%분비성중이염
myrtol standardized enteric coated soft capsules%dexamethasone%intratympanic injection%secretory otitis media
目的:观察标准桃金娘油肠溶胶囊口服联合地塞米松鼓室内注射治疗分泌性中耳炎的临床疗效。方法将医院收治的分泌性中耳炎100例患者随机分为对照组和观察组,各50例。两组患者均给予常规治疗,对照组患者在此基础上给予鼓膜穿刺抽液,地塞米松注射液鼓室内注射5 mg;盐酸麻黄碱滴鼻液滴鼻,2滴/次,3次/日;头孢拉定胶囊口服,每次0.5 g,3次/日。观察组患者在对照组基础上加服标准桃金娘油肠溶胶囊,每次300 mg,3次/日。两组患者均连续治疗4周。结果治疗后,观察组临床总有效率为87.50%,明显高于对照组的70.00%(P<0.05);观察组患者不同频率下纯音听阈测定气导听力、鼓室压及声阻抗鼓室压曲线改善程度明显优于对照组(P<0.05);治疗过程中,两组患者不良反应均较轻微,发生率无显著性差异(P>0.05),血、尿常规及肝、肾功能均未出现明显异常。结论标准桃金娘油肠溶胶囊联合地塞米松鼓室内注射可有效缓解耳闷塞、耳鸣等临床症状,并能显著提高患者纯音听阈测定气导听力水平,提高鼓室压,有效改善声阻抗鼓室压曲线,促进患者听力恢复。
目的:觀察標準桃金孃油腸溶膠囊口服聯閤地塞米鬆鼓室內註射治療分泌性中耳炎的臨床療效。方法將醫院收治的分泌性中耳炎100例患者隨機分為對照組和觀察組,各50例。兩組患者均給予常規治療,對照組患者在此基礎上給予鼓膜穿刺抽液,地塞米鬆註射液鼓室內註射5 mg;鹽痠痳黃堿滴鼻液滴鼻,2滴/次,3次/日;頭孢拉定膠囊口服,每次0.5 g,3次/日。觀察組患者在對照組基礎上加服標準桃金孃油腸溶膠囊,每次300 mg,3次/日。兩組患者均連續治療4週。結果治療後,觀察組臨床總有效率為87.50%,明顯高于對照組的70.00%(P<0.05);觀察組患者不同頻率下純音聽閾測定氣導聽力、鼓室壓及聲阻抗鼓室壓麯線改善程度明顯優于對照組(P<0.05);治療過程中,兩組患者不良反應均較輕微,髮生率無顯著性差異(P>0.05),血、尿常規及肝、腎功能均未齣現明顯異常。結論標準桃金孃油腸溶膠囊聯閤地塞米鬆鼓室內註射可有效緩解耳悶塞、耳鳴等臨床癥狀,併能顯著提高患者純音聽閾測定氣導聽力水平,提高鼓室壓,有效改善聲阻抗鼓室壓麯線,促進患者聽力恢複。
목적:관찰표준도금낭유장용효낭구복연합지새미송고실내주사치료분비성중이염적림상료효。방법장의원수치적분비성중이염100례환자수궤분위대조조화관찰조,각50례。량조환자균급여상규치료,대조조환자재차기출상급여고막천자추액,지새미송주사액고실내주사5 mg;염산마황감적비액적비,2적/차,3차/일;두포랍정효낭구복,매차0.5 g,3차/일。관찰조환자재대조조기출상가복표준도금낭유장용효낭,매차300 mg,3차/일。량조환자균련속치료4주。결과치료후,관찰조림상총유효솔위87.50%,명현고우대조조적70.00%(P<0.05);관찰조환자불동빈솔하순음은역측정기도은력、고실압급성조항고실압곡선개선정도명현우우대조조(P<0.05);치료과정중,량조환자불량반응균교경미,발생솔무현저성차이(P>0.05),혈、뇨상규급간、신공능균미출현명현이상。결론표준도금낭유장용효낭연합지새미송고실내주사가유효완해이민새、이명등림상증상,병능현저제고환자순음은역측정기도은력수평,제고고실압,유효개선성조항고실압곡선,촉진환자은력회복。
Objective To observe the clinical effect of myrtol standardized enteric coated soft capsules combined with intratympanic dexam-ethasone injection for treating secretory otitis media.Methods Totally 100 patients with secretory otitis media admitted to the hospital were randomly divided into the control group and the observation group,50 cases in each group.The two groups were given routine treatment,on this basis,the control group were given tympanic membrane puncture,dexamethasone (intratympanic injection of 5 mg);hy-drochloric acid ephedrine nasal drops (nasal drip 2 drops/time,3 times daily);cephalosporins (oral,0.5 g/time,3 times daily);the ob-servation group was added myrtol standardized enteric coated soft capsules (oral,300 mg/time,3 times daily)on the basis of the control group.The two groups were treated continuously for 4 weeks.Results After treatment,the total effective rate of the observation group was 87.50%,which was significantly higher than 70.00% of the control group (P <0.05);the improvement of air conduction hearing determined by pure tone hearing threshold under different frequency,middle ear pressure and acoustic impedance middle ear pressure curve in the observation group were significantly better than those of the control group (P <0.05);during the treatment,the adverse reactions in the two groups were mild,the incidence had no statistical difference (P >0.05);there were no obvious abnormal appeared in blood routine,routine urine examination,liver function,kidney function.Conclusion Myrtol standardized enteric coated soft capsules combined with intratympanic dexamethasone injection for treating secretory otitis media can effectively alleviate the ear stuffy plug and tinnitus,and can significantly improve air conduction hearing level determined by pure tone hearing threshold,improve tympanic pressure and the acoustic impedance of the tympanic cavity pressure curve,promote the recovery of patients′hearing.