CAJ | 학술논문

目的：探讨声触诊组织定量技术（VTQ）对浸润性乳腺癌误诊的相关因素，提高VTQ技术对浸润性乳腺癌的诊断价值。方法回顾性分析2013年1月～2014年7月142例经手术病理证实的浸润性乳腺癌病例。所有患者均进行常规超声和VTQ检查。以VTQ检查中乳腺病灶剪切波速度值（SWV）为7．303 m／s为良恶性占位的诊断截断值，根据诊断结果分析比较相关特征。结果142例浸润性癌中，误诊病例为27例（SWV值＜7．303 m／s），正确诊断病例为115例（SWV值≥7．303 m／s）。分析浸润性癌的各项特征结果显示肿块最大直径≤10 mm，肿瘤组织学分级I级，淋巴结转移阴性，Ki－67＜14％的浸润性乳腺癌较易被误诊为良性肿块；而患者年龄、肿块深度、ER、PR、HER－2对于浸润性癌的误诊没有明显统计学意义。肿块直径≥10 mm的单纯性黏液癌易被误诊为良性肿块。结论应用VTQ技术评价浸润性乳腺癌：肿瘤最大直径小于10 mm、肿瘤组织学分级Ⅰ级、Ki－67小于14％、淋巴结转移阴性的肿块较易被误诊为良性肿块；肿块直径超过10 mm的单纯性黏液癌易被误诊为良性肿块。
목적：탐토성촉진조직정량기술（VTQ）대침윤성유선암오진적상관인소，제고VTQ기술대침윤성유선암적진단개치。방법회고성분석2013년1월～2014년7월142례경수술병리증실적침윤성유선암병례。소유환자균진행상규초성화VTQ검사。이VTQ검사중유선병조전절파속도치（SWV）위7．303 m／s위량악성점위적진단절단치，근거진단결과분석비교상관특정。결과142례침윤성암중，오진병례위27례（SWV치＜7．303 m／s），정학진단병례위115례（SWV치≥7．303 m／s）。분석침윤성암적각항특정결과현시종괴최대직경≤10 mm，종류조직학분급I급，림파결전이음성，Ki－67＜14％적침윤성유선암교역피오진위량성종괴；이환자년령、종괴심도、ER、PR、HER－2대우침윤성암적오진몰유명현통계학의의。종괴직경≥10 mm적단순성점액암역피오진위량성종괴。결론응용VTQ기술평개침윤성유선암：종류최대직경소우10 mm、종류조직학분급Ⅰ급、Ki－67소우14％、림파결전이음성적종괴교역피오진위량성종괴；종괴직경초과10 mm적단순성점액암역피오진위량성종괴。
Objective To review causes of diagnostic errors of virtual touch tissues quantification (VTQ) in invasive breast cancer. Methods Pre-operative VTQ of 142 consecutive patients with breast cancer from January 2013 to July 2014 was reviewed. Characteristics of 27 invasive cancer with SWV values <7.303 m/s were compared with that of 115 cancer with SWV values ≥7.303 m/s. Results The invasive carcinoma with SWV values<7.303 m/s was smaller than 10 mm with grade I tumor histology, no lymph node metastasis and Ki-67<14%. There was no significant difference in the patient age, tumor depth, ER, PR, and HER-2 receptors..Mucinous carcinomas larger than 10 mm were more likely to be misdiagnosed as benign tumor. Conclusion Mucinous carcinomas larger than 10 mm and invasive breast cancer smaller than 10 mmwith grade I tumor histology , no lymph node metastasis and Ki-67<14%are more likely to be misdiagnosed as benign on VTQ.