CAJ | 학술논문

目的：：研究空腹血糖正常的门诊原发性高血压患者糖代谢异常临床特征，揭示糖耐量异常与血脂、尿酸及颈动脉粥样硬化的情况。方法：选择确诊有原发性高血压而无糖尿病的患者436例，入选患者口服葡萄糖耐量实验测定，分析年龄、性别、体重指数、血脂水平、颈动脉粥样硬化等参数与糖耐量异常的关系。结果：436例患者中检出糖耐量减低患者127例，占29.1%，糖尿病患者41例，占9.5%，糖耐量异常与性别、年龄、血尿酸水平、低密度脂蛋白、颈动脉粥样硬化呈正相关。结论：空腹血糖正常的门诊高血压患者合并糖耐量异常比例较高，常伴有血脂、尿酸及动脉粥样硬化等高危因素，应及早预防及治疗糖代谢异常及相关危险因素，从而减少糖尿病及心血管疾病发病风险。
목적：：연구공복혈당정상적문진원발성고혈압환자당대사이상림상특정，게시당내량이상여혈지、뇨산급경동맥죽양경화적정황。방법：선택학진유원발성고혈압이무당뇨병적환자436례，입선환자구복포도당내량실험측정，분석년령、성별、체중지수、혈지수평、경동맥죽양경화등삼수여당내량이상적관계。결과：436례환자중검출당내량감저환자127례，점29.1%，당뇨병환자41례，점9.5%，당내량이상여성별、년령、혈뇨산수평、저밀도지단백、경동맥죽양경화정정상관。결론：공복혈당정상적문진고혈압환자합병당내량이상비례교고，상반유혈지、뇨산급동맥죽양경화등고위인소，응급조예방급치료당대사이상급상관위험인소，종이감소당뇨병급심혈관질병발병풍험。
Objective:To investigate the factors that influence glucose tolerance in essential hypertention,identify the clinical characteristics of abnormal metabalism.Methods:436 outpatients with essential hypertention,with no history of diabites mellitus and normol fasting blood glucose were recruited.All eligible patients received oral glucose tolerance test. We analyzed the relationships between impaired glucose tolerance and other variables including age,gender,body mass index, blood pressure,uric acid,lipid levels,and carotid atherosclerosis plague.Results:Among 436 patients,the number of patients with impaired glucose tolerance was 127 (29.1%),the number of newly diagnosed diabites DM was 41 (9.5%).A positive correlation exists between glucose tolerance and other variables including age,gender,lowdensity cholesterol,uric acid and carotid atherosclerosis plague.Conclusion:High prevalence of abnormal glucose tolerance was discoved in essential hypertention patients with normol fasting blood glucose.Oral glucose tolerance test should be actively engaged in those patients to detect impaired glucose toleranc early.And it is helpful to postpone progression of diabites and reduce risk of cardelvassculer and cerebrovassculer disease.