医学研究杂志
醫學研究雜誌
의학연구잡지
Journal of Medical Research
2015年
10期
161-163
,共3页
实时三维超声心动图%螺内酯%高血压性心脏病
實時三維超聲心動圖%螺內酯%高血壓性心髒病
실시삼유초성심동도%라내지%고혈압성심장병
Real time 3-dimensional echocardiography%Spironolactone%Hypertensive heart disease
目的 探讨实时三维超声心动图( real time 3-dimensional echocardiography , RT-3DE)对螺内酯治疗高血压性心脏病的效果评价. 方法 以笔者医院2011年1月~2012年1月间收治的高血压性心脏病患者104例为研究对象,随机分为对照组和观察组,所有患者均行常规治疗,观察组在此基础上口服螺内酯,比较两组患者心室形态学指标和功能学指标之间的差异. 并探讨RT-3DE评价心室重构程度指标LVRI( left ventricular remodeling index )与胱抑素C( cystatin C, CysC)之间的相关性. 结果 观察组患者左心室舒张末期容积(left ventricular end-diastolic volume, LVEDV)、左心室收缩末期容积(left ventricular end systolic volume, LVESV)和左心室射血分数(left ventricular ejection fraction, LVEF)等心室形态和功能学指标较对照组有改善(P<0.05),CysC和LVRI都显示观察组患者心室重构程度更低(P<0.05),无论在观察组还是在对照组中,CysC和LVRI都具有良好相关性( r观察组 =0.913,r对照组 =0.856,P<0.05). 结论 螺内酯对于高血压性心脏病患者的心室重构有积极作用,RT-3DE能够从心室形态学和功能上双重评价对患者心室重构程度的影响.
目的 探討實時三維超聲心動圖( real time 3-dimensional echocardiography , RT-3DE)對螺內酯治療高血壓性心髒病的效果評價. 方法 以筆者醫院2011年1月~2012年1月間收治的高血壓性心髒病患者104例為研究對象,隨機分為對照組和觀察組,所有患者均行常規治療,觀察組在此基礎上口服螺內酯,比較兩組患者心室形態學指標和功能學指標之間的差異. 併探討RT-3DE評價心室重構程度指標LVRI( left ventricular remodeling index )與胱抑素C( cystatin C, CysC)之間的相關性. 結果 觀察組患者左心室舒張末期容積(left ventricular end-diastolic volume, LVEDV)、左心室收縮末期容積(left ventricular end systolic volume, LVESV)和左心室射血分數(left ventricular ejection fraction, LVEF)等心室形態和功能學指標較對照組有改善(P<0.05),CysC和LVRI都顯示觀察組患者心室重構程度更低(P<0.05),無論在觀察組還是在對照組中,CysC和LVRI都具有良好相關性( r觀察組 =0.913,r對照組 =0.856,P<0.05). 結論 螺內酯對于高血壓性心髒病患者的心室重構有積極作用,RT-3DE能夠從心室形態學和功能上雙重評價對患者心室重構程度的影響.
목적 탐토실시삼유초성심동도( real time 3-dimensional echocardiography , RT-3DE)대라내지치료고혈압성심장병적효과평개. 방법 이필자의원2011년1월~2012년1월간수치적고혈압성심장병환자104례위연구대상,수궤분위대조조화관찰조,소유환자균행상규치료,관찰조재차기출상구복라내지,비교량조환자심실형태학지표화공능학지표지간적차이. 병탐토RT-3DE평개심실중구정도지표LVRI( left ventricular remodeling index )여광억소C( cystatin C, CysC)지간적상관성. 결과 관찰조환자좌심실서장말기용적(left ventricular end-diastolic volume, LVEDV)、좌심실수축말기용적(left ventricular end systolic volume, LVESV)화좌심실사혈분수(left ventricular ejection fraction, LVEF)등심실형태화공능학지표교대조조유개선(P<0.05),CysC화LVRI도현시관찰조환자심실중구정도경저(P<0.05),무론재관찰조환시재대조조중,CysC화LVRI도구유량호상관성( r관찰조 =0.913,r대조조 =0.856,P<0.05). 결론 라내지대우고혈압성심장병환자적심실중구유적겁작용,RT-3DE능구종심실형태학화공능상쌍중평개대환자심실중구정도적영향.
Objective To investigate the effect evaluation of spironolactone in the treatment of hypertensive heart disease by the real time 3-dimensional echocardiography .Methods Totally 104 patients with hypertensive heart disease were in the study from Jan 2011 to Jan 2012 of our department and divided into objective group and control group .Conventional treatments were put in all the patients and the spironolactone was used in objective group patients only .The results of ventricular morphology and function indexes were compared be -tween the two groups, and then investigate the relationship between cystatin C (CycC) and left ventricular remodeling index (LVRI) at the same time.Results There were significant differences in the comparison of ventricular morphology and function indexes .The left ventric-ular end-diastolic volume(LVEDV), left ventricular end systolic volume (LVESV) and left ventricular ejection fraction (LVEF) of ob-jective group were more advantageous than flowse of control group for prognosis .The same results were observed in the comparison of Cys C and LVRI.Moreover, Cyc C and LVRI had certain correlation in the study .Conclusion The spironolactone can play a positive role in the treatment for the patients with hypertensive heart disease .In the meantime, the RT-3DE is a good evaluation method for the develop-ment of ventricular morphology and function .
