医学研究杂志
醫學研究雜誌
의학연구잡지
Journal of Medical Research
2015年
10期
60-63
,共4页
前列腺肿瘤%经直肠超声检查%弹性成像%磁共振成像%穿刺活检
前列腺腫瘤%經直腸超聲檢查%彈性成像%磁共振成像%穿刺活檢
전렬선종류%경직장초성검사%탄성성상%자공진성상%천자활검
Prostate cancer%Transrectal ultrasound%Elastography%Magnetic resonance imaging%Biopsy
目的 评价经直肠超声弹性成像、磁共振动态增强及联合应用对前列腺良恶性病变诊断的临床应用. 方法 对60例血清PSA水平高于4.0ng/ml的男性(43~83岁,平均年龄71岁)分别行经直肠超声检查 (transrectal ultrasound,TRUS),经直肠实时组织超声弹性成像(transrectal real-time elastography,TRTE)及磁共振动态增强检查(dynamic contrast material -enhanced magnetic resonance imaging ,DCE-MRI). 随后,对这些患者上述检查阳性征象部位针对性靶向活检,同时行常规6针活检,分别比较3种检查方法的前列腺癌阳性检出率. 结果 60例患者中23例为前列腺癌(23/60,38.3%). TRTE、DCE-MRI及两者联合对于诊断前列腺周缘区恶性病灶的敏感度、特异性及准确性分别为73.9%、78.3%、87.0%,80.1%、75.1%、89.2%及78.3%、76.7%、88.3%. 与TRUS比较,TRTE及DCE-MRI引导下的靶向穿刺活检提高前列腺癌的阳性检出率( P<0.05). 结论TRTE、DCE-MRI检查能够提高对血PSA升高患者前列腺癌病灶的检出率,从而提高前列腺穿刺活检的阳性率,为临床诊断提供强有力的诊断依据.
目的 評價經直腸超聲彈性成像、磁共振動態增彊及聯閤應用對前列腺良噁性病變診斷的臨床應用. 方法 對60例血清PSA水平高于4.0ng/ml的男性(43~83歲,平均年齡71歲)分彆行經直腸超聲檢查 (transrectal ultrasound,TRUS),經直腸實時組織超聲彈性成像(transrectal real-time elastography,TRTE)及磁共振動態增彊檢查(dynamic contrast material -enhanced magnetic resonance imaging ,DCE-MRI). 隨後,對這些患者上述檢查暘性徵象部位針對性靶嚮活檢,同時行常規6針活檢,分彆比較3種檢查方法的前列腺癌暘性檢齣率. 結果 60例患者中23例為前列腺癌(23/60,38.3%). TRTE、DCE-MRI及兩者聯閤對于診斷前列腺週緣區噁性病竈的敏感度、特異性及準確性分彆為73.9%、78.3%、87.0%,80.1%、75.1%、89.2%及78.3%、76.7%、88.3%. 與TRUS比較,TRTE及DCE-MRI引導下的靶嚮穿刺活檢提高前列腺癌的暘性檢齣率( P<0.05). 結論TRTE、DCE-MRI檢查能夠提高對血PSA升高患者前列腺癌病竈的檢齣率,從而提高前列腺穿刺活檢的暘性率,為臨床診斷提供彊有力的診斷依據.
목적 평개경직장초성탄성성상、자공진동태증강급연합응용대전렬선량악성병변진단적림상응용. 방법 대60례혈청PSA수평고우4.0ng/ml적남성(43~83세,평균년령71세)분별행경직장초성검사 (transrectal ultrasound,TRUS),경직장실시조직초성탄성성상(transrectal real-time elastography,TRTE)급자공진동태증강검사(dynamic contrast material -enhanced magnetic resonance imaging ,DCE-MRI). 수후,대저사환자상술검사양성정상부위침대성파향활검,동시행상규6침활검,분별비교3충검사방법적전렬선암양성검출솔. 결과 60례환자중23례위전렬선암(23/60,38.3%). TRTE、DCE-MRI급량자연합대우진단전렬선주연구악성병조적민감도、특이성급준학성분별위73.9%、78.3%、87.0%,80.1%、75.1%、89.2%급78.3%、76.7%、88.3%. 여TRUS비교,TRTE급DCE-MRI인도하적파향천자활검제고전렬선암적양성검출솔( P<0.05). 결론TRTE、DCE-MRI검사능구제고대혈PSA승고환자전렬선암병조적검출솔,종이제고전렬선천자활검적양성솔,위림상진단제공강유력적진단의거.
Objective To compare the value of transrectal real -time elastography ( TRTE) with dynamic contrast material -en-hanced magnetic resonance imaging (DCE-MRI) for prostate cancer detection.Methods A total of 60 men (mean age 71years, range 43 to 83) with serum PSA levels of greater than 4.0ng/ml were assessed using gray -scale transrectal ultrasound (TRUS), transrectal real-time elastography ( TRTE ) and dynamic contrast material -enhanced magnetic resonance imaging ( DCE -MRI ) .Subsequently , these patients underwent systematic sextant transrectal biopsy and additional biopsies for positive sites on gray -scale TRUS, TRTE and DCE-MRI.The cancer detection rates of the 3 techniques were compared .Results Cancer was detected in 23 of the 60 patients (23/60,38.3%).TRTE and DCE-MRI had a higher sensitivity, specificity and accuracy of 73.9%,78.3%,87.0%,80.1%,75.1%, 89.2%,78.3%,76.7%,88.3%respectively.TRTE and DCE-MRI guided targeted biopsy improve the positive detection rate of pros-tate cancer, compared with TRUS (P<0.05).Conclusion TRTE and DCE-MRI can improve the detection rate of the increase of ser-um PSA in patients with prostate cancer , so as to improve the positive rate of prostate biopsy diagnosis ,provide strong support for clinical diagnosis
