CAJ | 학술논문

目的：探讨不同医师操作下，超声引导下细针抽吸细胞学检查（fine needle aspiration cytology，FNAC）对不同大小甲状腺结节的诊断价值。方法回顾性分析109例患者122个结节的FNAC结果与手术组织病理学结果。结果17个结节（13.9%）未获得满意的细胞学诊断结果，余105个结节FNAC与组织学结果的符合率85.7%。诊断敏感性78.6%，特异性93.9%，阳性预测值93.6%，阴性预测值79.3%。≤1 cm与＞1 cm组只有阴性预测值差异有统计学意义。≤1 cm与＞1 cm组、良恶性结节间、不同医师操作下FNAC取材不满意率均无统计学差异。结论 FNAC能有效鉴别不同大小甲状腺结节良恶性。
목적：탐토불동의사조작하，초성인도하세침추흡세포학검사（fine needle aspiration cytology，FNAC）대불동대소갑상선결절적진단개치。방법회고성분석109례환자122개결절적FNAC결과여수술조직병이학결과。결과17개결절（13.9%）미획득만의적세포학진단결과，여105개결절FNAC여조직학결과적부합솔85.7%。진단민감성78.6%，특이성93.9%，양성예측치93.6%，음성예측치79.3%。≤1 cm여＞1 cm조지유음성예측치차이유통계학의의。≤1 cm여＞1 cm조、량악성결절간、불동의사조작하FNAC취재불만의솔균무통계학차이。결론 FNAC능유효감별불동대소갑상선결절량악성。
[ABSTRACT]OBJECTIVETo evaluate the clinical value of ultrasound guided fine-needle aspiration (US-FNA) in the diagnosis of thyroid nodules with different size.METHODSThe clinical data of 122 thyroid nodules of 109 cases referred to FNAC for diagnosis were retrospectively reviewed. The final operating histological results of 122 nodules were considered gold standard. RESULTSNon-diagnostic FNAC results occurred in 17 nodules (13.9%). FNAC achieved a sensitivity of 78.6%, a specificity of 93.9%, a positive predictive value of 93.6%, a negative predictive value of 78.3%, and a total accuracy of 85.7%. There was no significant difference between the diameter of the nodule≤1 cm group and>1 cm group, except negative predictive value. The non-diagnostic results rate was no significant difference between groups of different nodule size, benign or malignant nodules, and different operators. CONCLUSIONFNAC is a sensitive, specific and accurate method for differential diagnosis of thyroid nodules.